Phosphodiesterase function and regulation
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Scope of this subject
This cluster of papers focuses on the molecular regulation and clinical applications of cyclic nucleotide phosphodiesterases (PDEs), particularly in the context of cAMP signaling, schizophrenia genetics, neuronal development, therapeutic targeting, compartmentalized signaling, Alzheimer's disease treatment, cardiac function regulation, and the development of phosphodiesterase inhibitors.
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Research vocabulary
phosphodiesterase inhibitors; phosphodiesterase; cyclic nucleotide phosphodiesterase; cyclic nucleotides; phosphodiesterase-4 inhibitors; phosphodiesterase 4; rolipram; cyclic AMP phosphodiesterase; phosphodiesterase inhibition; phosphodiesterase 5; PDE10A; PDE4D; phosphodiesterase 3; cAMP phosphodiesterase; PDE4B; cAMP hydrolysis; phosphodiesterase III inhibitor; PDE2; cGMP hydrolysis; cGMP phosphodiesterase; cyclic GMP phosphodiesterase; zaprinast; PDE3A; PDE1; cyclic AMP hydrolysis
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Numeric address and provenance
Morton address: 38285014211240579 · morton4x16-v1
Coordinates: (1, 13, 1312, 12434). The address interleaves categorical identifier bits. Nearby addresses are not guaranteed to describe semantically similar subjects.
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