# Phosphodiesterase function and regulation { "id": "T12434", "title": "Phosphodiesterase function and regulation", "url": "/topics/T12434", "kind": "topic-directory", "aeo_cohort": "topic-directory", "provider": "openalex", "revision": "9db084e2e05e0579", "catalogue_revision": "f050b5d4780b1289", "numeric_address": "38285014211240579", "address_version": "morton4x16-v1", "coordinates": [ 1, 13, 1312, 12434 ], "answer_status": "Directory metadata; local answer requires separate source review", "truth_status": "Subject descriptor, not a factual answer or a demonstrated knowledge gap" } This cluster of papers focuses on the molecular regulation and clinical applications of cyclic nucleotide phosphodiesterases (PDEs), particularly in the context of cAMP signaling, schizophrenia genetics, neuronal development, therapeutic targeting, compartmentalized signaling, Alzheimer's disease treatment, cardiac function regulation, and the development of phosphodiesterase inhibitors. Directory metadata is not a factual answer or evidence of a global knowledge gap. Source: https://openalex.org/T12434 No owner-reviewed local answer yet.