Complement system in diseases
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Scope of this subject
This cluster of papers explores the role of the complement system in immune response, focusing on its involvement in thrombotic microangiopathies, hemolytic uremic syndrome, and inflammatory diseases. It delves into the genetics, regulation, and therapeutic interventions such as Eculizumab for managing complement-related disorders.
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Research vocabulary
complement system; complement activation; thrombotic thrombocytopenic purpura; thrombotic microangiopathy; alternative complement pathway; hemolytic uremic syndrome; paroxysmal nocturnal hemoglobinuria; complement C3; eculizumab; atypical hemolytic uremic syndrome; complement inhibition; complement regulation; microangiopathic hemolytic anemia; complement factor H; membrane attack complex; classical complement pathway; C1q; complement regulatory proteins; ADAMTS13; C5a; mannose-binding lectin; factor B; CD55; CD59; properdin
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Numeric address and provenance
Morton address: 36240472549236813 · morton4x16-v1
Coordinates: (1, 24, 2403, 10993). The address interleaves categorical identifier bits. Nearby addresses are not guaranteed to describe semantically similar subjects.
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