# Complement system in diseases { "id": "T10993", "title": "Complement system in diseases", "url": "/topics/T10993", "kind": "topic-directory", "aeo_cohort": "topic-directory", "provider": "openalex", "revision": "df84063b2adeb8f9", "catalogue_revision": "f050b5d4780b1289", "numeric_address": "36240472549236813", "address_version": "morton4x16-v1", "coordinates": [ 1, 24, 2403, 10993 ], "answer_status": "Directory metadata; local answer requires separate source review", "truth_status": "Subject descriptor, not a factual answer or a demonstrated knowledge gap" } This cluster of papers explores the role of the complement system in immune response, focusing on its involvement in thrombotic microangiopathies, hemolytic uremic syndrome, and inflammatory diseases. It delves into the genetics, regulation, and therapeutic interventions such as Eculizumab for managing complement-related disorders. Directory metadata is not a factual answer or evidence of a global knowledge gap. Source: https://openalex.org/T10993 No owner-reviewed local answer yet.