Phagocytosis and Immune Regulation
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Scope of this subject
This cluster of papers focuses on the mechanisms and regulation of apoptotic cell clearance, including the role of CD47, phagocytosis, TAM receptors, efferocytosis, and the implications for cancer immunotherapy. It explores the involvement of various molecules and pathways in the recognition and removal of apoptotic cells by phagocytes, shedding light on potential therapeutic targets for immune-related diseases.
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Research vocabulary
efferocytosis; CD47; SIRPα; apoptotic cells; MERTK; anti-CD47 antibody; CD47 blockade; phagocytosis of apoptotic cells; TAM receptors; eat-me signals; apoptotic neutrophils; don't eat me signal; phosphatidylserine receptor; innate immune checkpoint; phagocytic receptors; CD47-SIRPα axis; macrophage efferocytosis; phagosome formation; apoptotic cell recognition; apoptotic cell engulfment; neutrophil clearance; anti-CD47 monoclonal antibody; CD47-SIRPα interaction; tumor phagocytosis; find-me signals
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Numeric address and provenance
Morton address: 38351019335360581 · morton4x16-v1
Coordinates: (1, 24, 2403, 12672). The address interleaves categorical identifier bits. Nearby addresses are not guaranteed to describe semantically similar subjects.
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