Coagulation, Bradykinin, Polyphosphates, and Angioedema
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Scope of this subject
This cluster of papers focuses on the molecular mechanisms, pathophysiological consequences, and clinical management of Hereditary Angioedema. It covers topics such as the role of kinin receptors, coagulation factors XII and XI, polyphosphate, C1 inhibitor deficiency, and the use of bradykinin-receptor antagonists in the treatment of angioedema. Additionally, it explores the involvement of tissue kallikreins and the contact activation system in the disease pathology.
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Research vocabulary
bradykinin; hereditary angioedema; kallikrein-kinin system; C1 inhibitor deficiency; angioedema; C1 inhibitor; kallikrein; bradykinin B2 receptor; factor XII; kinins; high molecular weight kininogen; prekallikrein; kininogen; plasma kallikrein; icatibant; factor XI; bradykinin receptor antagonists; contact activation; bradykinin B1 receptor; drug-induced angioedema; bradykinin receptors; acquired angioedema; tissue kallikrein; des-Arg9-bradykinin; factor XI deficiency
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Numeric address and provenance
Morton address: 36249527199919402 · morton4x16-v1
Coordinates: (4, 27, 2716, 11917). The address interleaves categorical identifier bits. Nearby addresses are not guaranteed to describe semantically similar subjects.
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