Chemical Reactions and Isotopes
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Scope of this subject
This cluster of papers focuses on the use of deuterium and tritium labeling, hydrogen isotope exchange, and catalysis in drug discovery and development. It explores applications in medicinal chemistry, metabolism studies, and the incorporation of deuterium into pharmaceutical compounds. The research also highlights the use of iridium-catalyzed reactions and the impact of deuterium substitution on drug pharmacokinetics.
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Research vocabulary
tritium labeling; carbon-14 labeling; radiolabeled compounds; hydrogen isotope exchange; isotopically labeled compounds; radiolabeled compound synthesis; isotope exchange kinetics; high specific activity; labeled compounds; tritium exchange; radiotracer preparation; isotopic purity; carbon-13 labelling; tritiated compounds; deuterium-depleted water; tritium-labeled compounds; radiolabeled synthesis; deuterated drugs; radiolabeled steroids; heavy water production; deuterated amino acids; hot atom chemistry; catalytic exchange; isotopic synthesis; tritium incorporation
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Numeric address and provenance
Morton address: 38360057096626797 · morton4x16-v1
Coordinates: (1, 30, 3003, 13561). The address interleaves categorical identifier bits. Nearby addresses are not guaranteed to describe semantically similar subjects.
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