Synthesis and pharmacology of benzodiazepine derivatives
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Scope of this subject
This cluster of papers focuses on the chemistry, synthesis, and biological evaluation of pyrrolobenzodiazepines, a class of DNA-interactive agents with potent antitumour activity. The research covers topics such as asymmetric synthesis, cross-linking agents, cytotoxicity, and their application in natural product synthesis.
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Research vocabulary
1,4-benzodiazepines; benzodiazepine derivatives; 1,5-benzodiazepines; benzodiazepine synthesis; pyrrolo[2,1-c][1,4]benzodiazepines; benzodiazepinones; CC-1065; pyrrolobenzodiazepine; fused benzodiazepines; duocarmycin; pyrrolobenzodiazepine dimer; 1,4-benzodiazepin-2-ones; 1,5-benzodiazepine derivatives; benzodiazepine analogues; diazepine synthesis; anthramycin; fused diazepines; triazolobenzodiazepines; tetrahydrobenzodiazepines; 2,3-benzodiazepines; 1,4-diazepines; SJG-136; dibenzodiazepines; duocarmycin SA; diazepine derivatives
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Morton address: 38285853948773405 · morton4x16-v1
Coordinates: (3, 16, 1605, 13105). The address interleaves categorical identifier bits. Nearby addresses are not guaranteed to describe semantically similar subjects.
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