Porphyrin Metabolism and Disorders
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This cluster of papers explores the molecular mechanisms of heme biosynthesis, including the catalysis by cobalamin-dependent enzymes, genetic mutations leading to porphyrias, microbial production of vitamin B12, and the use of RNA interference therapy and liver transplantation for the treatment of related disorders. It also delves into metabolic engineering and genomic analysis related to heme biosynthesis pathways.
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Research vocabulary
porphyria; heme biosynthesis; acute intermittent porphyria; porphyria cutanea tarda; porphobilinogen; erythropoietic protoporphyria; porphyrin metabolism; vitamin B12 biosynthesis; acute porphyria; porphyria cutanea acuta; delta-aminolevulinic acid dehydratase; variegate porphyria; coproporphyrin; porphobilinogen deaminase; delta-aminolevulinic acid synthase; uroporphyrin; ferrochelatase; hepatic porphyria; congenital erythropoietic porphyria; cutaneous porphyria; urinary porphyrins; uroporphyrinogen decarboxylase; tetrapyrrole biosynthesis; porphyria treatment; acute hepatic porphyria
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Morton address: 38285014211273227 · morton4x16-v1
Coordinates: (1, 13, 1312, 12441). The address interleaves categorical identifier bits. Nearby addresses are not guaranteed to describe semantically similar subjects.
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