Cholesterol and Lipid Metabolism
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Scope of this subject
This cluster of papers focuses on the intricate mechanisms of cholesterol metabolism, including the roles of key regulators such as LXR and SREBP, the impact on atherosclerosis, and the involvement of specific proteins like ABCA1 in processes such as cholesterol efflux from cells. It also delves into the effects of phytosterols on lipid levels and the interplay between cholesterol homeostasis and inflammation in conditions like atherosclerosis.
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Research vocabulary
apolipoprotein A-I; cholesterol biosynthesis; cholesterol metabolism; high-density lipoprotein; cholesterol efflux; ABCA1; reverse cholesterol transport; LDL receptor; lipoprotein metabolism; dietary cholesterol; cholesterol esters; cholesterol homeostasis; HMG-CoA reductase; cholesterol absorption; cholesterol esterification; bile acid synthesis; lecithin:cholesterol acyltransferase; free cholesterol; foam cells; scavenger receptor class B type I; CYP7A1; cholesteryl ester transfer protein; liver X receptor; ABCG1; oxysterols
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Numeric address and provenance
Morton address: 36249009803125218 · morton4x16-v1
Coordinates: (4, 27, 2746, 11618). The address interleaves categorical identifier bits. Nearby addresses are not guaranteed to describe semantically similar subjects.
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