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Click Chemistry and Applications

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Scope of this subject

This cluster of papers focuses on the application of click chemistry, particularly the copper-catalyzed azide-alkyne cycloaddition, in chemical biology and drug development. It explores diverse chemical functionality, bioorthogonal chemistry, protein labeling, in vivo imaging, triazole synthesis, and the development of enzyme inhibitors.

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Research vocabulary

click chemistry; 1,2,3-triazoles; copper-catalyzed azide-alkyne cycloaddition; azide-alkyne cycloaddition; bioorthogonal chemistry; triazole synthesis; 1,4-disubstituted triazoles; strain-promoted azide-alkyne cycloaddition; bioorthogonal labeling; bioorthogonal reactions; trans-cyclooctene; copper-free click chemistry; cyclooctyne; site-specific protein modification; site-specific protein labeling; bioorthogonal click chemistry; Huisgen 1,3-dipolar cycloaddition; 1,2,3-triazole synthesis; bioorthogonal ligation; Staudinger ligation; benzyl azide; live cell labeling; tetrazine ligation; 1,4-disubstituted 1,2,3-triazoles; click reaction

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Morton address: 36183005748397077 · morton4x16-v1

Coordinates: (3, 16, 1605, 11440). The address interleaves categorical identifier bits. Nearby addresses are not guaranteed to describe semantically similar subjects.

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