Statistical Methods in Clinical Trials
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Scope of this subject
This cluster of papers covers a wide range of statistical methods and design considerations in the context of clinical trials and drug development. It includes topics such as controlling the false discovery rate, adaptive trial designs, noninferiority trials, biomarkers, phase I trials, multiple testing, Bayesian methods, sample size determination, composite endpoints, and pharmacokinetic/pharmacodynamic modeling.
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Research vocabulary
clinical trial design; sample size determination; trial design; multiple comparisons; cancer clinical trials; treatment effect estimation; interim analysis; adaptive trial design; type I error control; early stopping; family-wise error rate; time-to-event outcomes; blinding; adaptive design; group sequential designs; equivalence testing; type I error rate; composite endpoints; covariate adjustment; sample size reduction; treatment allocation; dose-finding; continuous outcomes; stopping boundaries; two-stage design
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Local answer status
No owner-reviewed answer has been published for this exact subject page. This is a gap in this collection; it does not establish that the answer is unavailable elsewhere.
Numeric address and provenance
Morton address: 36240764539643069 · morton4x16-v1
Coordinates: (3, 26, 2613, 11235). The address interleaves categorical identifier bits. Nearby addresses are not guaranteed to describe semantically similar subjects.
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