PI3K/AKT/mTOR signaling in cancer
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Scope of this subject
This cluster of papers focuses on the mTOR signaling pathway, particularly its role in growth control, metabolism, and disease, with a specific emphasis on cancer. The PI3K/AKT pathway, Raptor, TSC2, and rapamycin are central to the research discussed in these papers.
OpenAlex generated this cluster description with an LLM. It describes research grouping, not verified findings.
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Research vocabulary
mTORC1; PI3K inhibitors; PIK3CA mutation; mTORC2; 4E-BP1; AKT inhibitors; TOR signaling; PTEN loss; p70S6K; Rictor; PI3K inhibition; p70 S6 kinase; PDK1; alpelisib; PI3K/mTOR inhibitors; S6 phosphorylation; Rheb; S6K1; nutrient signaling; PI3Kα inhibitor; PI3K/mTOR dual inhibitor; TORC1; p110α; PI3Kα; MK-2206
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Local answer status
No owner-reviewed answer has been published for this exact subject page. This is a gap in this collection; it does not establish that the answer is unavailable elsewhere.
Numeric address and provenance
Morton address: 36174501775450627 · morton4x16-v1
Coordinates: (1, 13, 1312, 10952). The address interleaves categorical identifier bits. Nearby addresses are not guaranteed to describe semantically similar subjects.
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