# Hypertrophic osteoarthropathy and related conditions { "id": "T14057", "title": "Hypertrophic osteoarthropathy and related conditions", "url": "/topics/T14057", "kind": "topic-directory", "aeo_cohort": "topic-directory", "provider": "openalex", "revision": "397cf620638d51d2", "catalogue_revision": "f050b5d4780b1289", "numeric_address": "38360589672046894", "address_version": "morton4x16-v1", "coordinates": [ 4, 27, 2745, 14057 ], "answer_status": "Directory metadata; local answer requires separate source review", "truth_status": "Subject descriptor, not a factual answer or a demonstrated knowledge gap" } This cluster of papers focuses on primary hypertrophic osteoarthropathy and related conditions such as pachydermoperiostosis, digital clubbing, and small intestinal ulceration. It explores the genetic mutations, pathophysiology, clinical features, and treatment options for these conditions, with a particular emphasis on the role of prostaglandin transporter gene SLCO2A1 and vascular endothelial growth factor. Directory metadata is not a factual answer or evidence of a global knowledge gap. Source: https://openalex.org/T14057 No owner-reviewed local answer yet.