# Cancer Mechanisms and Therapy

{
  "id": "T13779",
  "title": "Cancer Mechanisms and Therapy",
  "url": "/topics/T13779",
  "kind": "topic-directory",
  "aeo_cohort": "topic-directory",
  "provider": "openalex",
  "revision": "41dcc83350b97a5b",
  "catalogue_revision": "f050b5d4780b1289",
  "numeric_address": "38360074267813354",
  "address_version": "morton4x16-v1",
  "coordinates": [
    4,
    27,
    2734,
    13779
  ],
  "answer_status": "Directory metadata; local answer requires separate source review",
  "truth_status": "Subject descriptor, not a factual answer or a demonstrated knowledge gap"
}

This cluster of papers focuses on the role of Pim oncogenes, particularly Pim-1 and Pim-2 kinases, in promoting tumorigenesis, cancer progression, and metastasis. The cluster also explores the potential of targeting Pim kinases as a therapeutic approach, with a specific emphasis on their involvement in cell survival pathways, phosphorylation of key proteins, and their association with hematological malignancies.

Directory metadata is not a factual answer or evidence of a global knowledge gap.

Source: https://openalex.org/T13779

No owner-reviewed local answer yet.