# Calcium signaling and nucleotide metabolism

{
  "id": "T13415",
  "title": "Calcium signaling and nucleotide metabolism",
  "url": "/topics/T13415",
  "kind": "topic-directory",
  "aeo_cohort": "topic-directory",
  "provider": "openalex",
  "revision": "048e32e6e989b74e",
  "catalogue_revision": "f050b5d4780b1289",
  "numeric_address": "38293808298863307",
  "address_version": "morton4x16-v1",
  "coordinates": [
    1,
    13,
    1314,
    13415
  ],
  "answer_status": "Directory metadata; local answer requires separate source review",
  "truth_status": "Subject descriptor, not a factual answer or a demonstrated knowledge gap"
}

This cluster of papers explores the evolution, function, and dysregulation of lysosomal calcium signaling, focusing on the role of two-pore channels, NAADP, TRPML1, and cyclic ADP-ribose in intracellular calcium release and endolysosomal trafficking. It also investigates the implications of these mechanisms in diseases such as mucolipidosis type IV and lysosomal storage disorders.

Directory metadata is not a factual answer or evidence of a global knowledge gap.

Source: https://openalex.org/T13415

No owner-reviewed local answer yet.