# Congenital limb and hand anomalies

{
  "id": "T13107",
  "title": "Congenital limb and hand anomalies",
  "url": "/topics/T13107",
  "kind": "topic-directory",
  "aeo_cohort": "topic-directory",
  "provider": "openalex",
  "revision": "5f9e2923c1207536",
  "catalogue_revision": "f050b5d4780b1289",
  "numeric_address": "38285596183783055",
  "address_version": "morton4x16-v1",
  "coordinates": [
    1,
    13,
    1309,
    13107
  ],
  "answer_status": "Directory metadata; local answer requires separate source review",
  "truth_status": "Subject descriptor, not a factual answer or a demonstrated knowledge gap"
}

This cluster of papers focuses on genetic and developmental studies of congenital limb anomalies, including polydactyly, syndactyly, and other malformations. It explores the genetic heterogeneity, mutations in CBP and EP300 genes, disruptions in Shh regulatory elements, upper extremity development, embryology, various classification systems, and epidemiological aspects related to limb anomalies.

Directory metadata is not a factual answer or evidence of a global knowledge gap.

Source: https://openalex.org/T13107

No owner-reviewed local answer yet.