# Animal testing and alternatives { "id": "T12281", "title": "Animal testing and alternatives", "url": "/topics/T12281", "kind": "topic-directory", "aeo_cohort": "topic-directory", "provider": "openalex", "revision": "6fdef2a05b096bdd", "catalogue_revision": "f050b5d4780b1289", "numeric_address": "36253701046322472", "address_version": "morton4x16-v1", "coordinates": [ 4, 34, 3404, 12281 ], "answer_status": "Directory metadata; local answer requires separate source review", "truth_status": "Subject descriptor, not a factual answer or a demonstrated knowledge gap" } This cluster of papers focuses on improving the reporting and conduct of animal research studies, with an emphasis on the use of ARRIVE guidelines, cytotoxicity assays, ethical considerations, systematic reviews, in vitro testing methods, and addressing publication bias. It also discusses the challenges in translating findings from animal studies to human applications and the determination of sample sizes for preclinical studies. Directory metadata is not a factual answer or evidence of a global knowledge gap. Source: https://openalex.org/T12281 No owner-reviewed local answer yet.