# S100 Proteins and Annexins { "id": "T12030", "title": "S100 Proteins and Annexins", "url": "/topics/T12030", "kind": "topic-directory", "aeo_cohort": "topic-directory", "provider": "openalex", "revision": "01a3e28291ac347a", "catalogue_revision": "f050b5d4780b1289", "numeric_address": "36183297877387907", "address_version": "morton4x16-v1", "coordinates": [ 1, 13, 1312, 12030 ], "answer_status": "Directory metadata; local answer requires separate source review", "truth_status": "Subject descriptor, not a factual answer or a demonstrated knowledge gap" } This cluster of papers focuses on the structure, function, and pathology of S100 proteins, a multigenic family of calcium-modulated proteins with roles in inflammation, neurodegeneration, cancer biomarkers, traumatic brain injury, innate immunity, glial fibrillary acidic protein, metastasis, and phagocytes. Directory metadata is not a factual answer or evidence of a global knowledge gap. Source: https://openalex.org/T12030 No owner-reviewed local answer yet.