# Melanoma and MAPK Pathways { "id": "T11533", "title": "Melanoma and MAPK Pathways", "url": "/topics/T11533", "kind": "topic-directory", "aeo_cohort": "topic-directory", "provider": "openalex", "revision": "4389d8c0dfa9ae2e", "catalogue_revision": "f050b5d4780b1289", "numeric_address": "36182780190697995", "address_version": "morton4x16-v1", "coordinates": [ 1, 13, 1312, 11533 ], "answer_status": "Directory metadata; local answer requires separate source review", "truth_status": "Subject descriptor, not a factual answer or a demonstrated knowledge gap" } This cluster of papers focuses on the mammalian MAP kinase signaling pathways, particularly their role in cancer, with a specific emphasis on melanoma. It covers the genetic mutations, targeted therapies, resistance mechanisms, and the impact of MAP kinase pathways on cell proliferation and immune response. Directory metadata is not a factual answer or evidence of a global knowledge gap. Source: https://openalex.org/T11533 No owner-reviewed local answer yet.