# Drug-Induced Adverse Reactions { "id": "T11117", "title": "Drug-Induced Adverse Reactions", "url": "/topics/T11117", "kind": "topic-directory", "aeo_cohort": "topic-directory", "provider": "openalex", "revision": "bf22989e00993ddc", "catalogue_revision": "f050b5d4780b1289", "numeric_address": "36240763465935146", "address_version": "morton4x16-v1", "coordinates": [ 4, 27, 2736, 11117 ], "answer_status": "Directory metadata; local answer requires separate source review", "truth_status": "Subject descriptor, not a factual answer or a demonstrated knowledge gap" } This cluster of papers focuses on hypersensitivity reactions to various drugs and medications, including the role of specific HLA genotypes such as HLA-B*5701, HLA-B*1502, and HLA-B*5801 in predicting severe cutaneous adverse reactions like Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis. The cluster also covers topics related to drug-induced hypersensitivity syndrome (DIHS), delayed drug hypersensitivity reactions, and the use of genetic screening to prevent abacavir hypersensitivity reactions. Directory metadata is not a factual answer or evidence of a global knowledge gap. Source: https://openalex.org/T11117 No owner-reviewed local answer yet.