# Ubiquitin and proteasome pathways { "id": "T11041", "title": "Ubiquitin and proteasome pathways", "url": "/topics/T11041", "kind": "topic-directory", "aeo_cohort": "topic-directory", "provider": "openalex", "revision": "c29a688b610a0dbf", "catalogue_revision": "f050b5d4780b1289", "numeric_address": "36174533861843467", "address_version": "morton4x16-v1", "coordinates": [ 1, 13, 1312, 11041 ], "answer_status": "Directory metadata; local answer requires separate source review", "truth_status": "Subject descriptor, not a factual answer or a demonstrated knowledge gap" } This cluster of papers focuses on the Ubiquitin-Proteasome Proteolytic Pathway, exploring mechanisms of protein degradation, regulation of E3 Ubiquitin Ligases, roles of Deubiquitinating Enzymes, and the impact of SUMOylation. It also delves into the development of proteasome inhibitors for cancer therapy and the involvement of this pathway in NF-?B activation. Directory metadata is not a factual answer or evidence of a global knowledge gap. Source: https://openalex.org/T11041 No owner-reviewed local answer yet.