# CRISPR and Genetic Engineering { "id": "T10878", "title": "CRISPR and Genetic Engineering", "url": "/topics/T10878", "kind": "topic-directory", "aeo_cohort": "topic-directory", "provider": "openalex", "revision": "ca250a8feff0ff93", "catalogue_revision": "f050b5d4780b1289", "numeric_address": "36174499636882051", "address_version": "morton4x16-v1", "coordinates": [ 1, 13, 1312, 10878 ], "answer_status": "Directory metadata; local answer requires separate source review", "truth_status": "Subject descriptor, not a factual answer or a demonstrated knowledge gap" } This cluster of papers focuses on the use of CRISPR-Cas systems for genome engineering, RNA-guided gene editing, and bacterial immunity. It covers topics such as Cas9 nucleases, off-target effects, multiplex genome editing, and genetic screening using CRISPR technology. Directory metadata is not a factual answer or evidence of a global knowledge gap. Source: https://openalex.org/T10878 No owner-reviewed local answer yet.