# Amyotrophic Lateral Sclerosis Research

{
  "id": "T10855",
  "title": "Amyotrophic Lateral Sclerosis Research",
  "url": "/topics/T10855",
  "kind": "topic-directory",
  "aeo_cohort": "topic-directory",
  "provider": "openalex",
  "revision": "4faf9007b624c790",
  "catalogue_revision": "f050b5d4780b1289",
  "numeric_address": "36240729105918378",
  "address_version": "morton4x16-v1",
  "coordinates": [
    4,
    27,
    2728,
    10855
  ],
  "answer_status": "Directory metadata; local answer requires separate source review",
  "truth_status": "Subject descriptor, not a factual answer or a demonstrated knowledge gap"
}

This cluster of papers focuses on the molecular mechanisms, genetics, and pathology of Amyotrophic Lateral Sclerosis (ALS) and Frontotemporal Dementia (FTD). It covers topics such as TDP-43, FUS/TLS, C9ORF72 mutations, neurodegeneration of motor neurons, RNA processing, progranulin deficiency, ubiquitin-positive inclusions, and the genetic underpinnings of these diseases.

Directory metadata is not a factual answer or evidence of a global knowledge gap.

Source: https://openalex.org/T10855

No owner-reviewed local answer yet.