# Cancer, Hypoxia, and Metabolism

{
  "id": "T10631",
  "title": "Cancer, Hypoxia, and Metabolism",
  "url": "/topics/T10631",
  "kind": "topic-directory",
  "aeo_cohort": "topic-directory",
  "provider": "openalex",
  "revision": "e0bd0cb2e8aae02e",
  "catalogue_revision": "f050b5d4780b1289",
  "numeric_address": "36173986241211083",
  "address_version": "morton4x16-v1",
  "coordinates": [
    1,
    13,
    1306,
    10631
  ],
  "answer_status": "Directory metadata; local answer requires separate source review",
  "truth_status": "Subject descriptor, not a factual answer or a demonstrated knowledge gap"
}

This cluster of papers explores the metabolic reprogramming in cancer cells, focusing on the role of hypoxia-inducible factor 1 (HIF-1), the Warburg effect, tumor hypoxia, glutamine metabolism, and the impact of the tumor microenvironment on cancer cell metabolism. It also delves into oxygen sensing, mitochondrial metabolism, glycolysis inhibition, and the role of hexokinase II in cancer progression.

Directory metadata is not a factual answer or evidence of a global knowledge gap.

Source: https://openalex.org/T10631

No owner-reviewed local answer yet.