# Psoriasis: Treatment and Pathogenesis { "id": "T10469", "title": "Psoriasis: Treatment and Pathogenesis", "url": "/topics/T10469", "kind": "topic-directory", "aeo_cohort": "topic-directory", "provider": "openalex", "revision": "a3e89a110a506d2d", "catalogue_revision": "f050b5d4780b1289", "numeric_address": "36239922792900685", "address_version": "morton4x16-v1", "coordinates": [ 1, 24, 2403, 10469 ], "answer_status": "Directory metadata; local answer requires separate source review", "truth_status": "Subject descriptor, not a factual answer or a demonstrated knowledge gap" } This cluster of papers focuses on the reciprocal developmental pathways for the generation of pathogenic effector TH17 cells and regulatory T cells, particularly in the context of autoimmune inflammation, interleukin-23, psoriasis, and the role of cytokines such as TGF-ß. It also explores the differentiation, cytokine profile, and function of human interleukin 17–producing helper T cells. Directory metadata is not a factual answer or evidence of a global knowledge gap. Source: https://openalex.org/T10469 No owner-reviewed local answer yet.