# Lung Cancer Treatments and Mutations { "id": "T10417", "title": "Lung Cancer Treatments and Mutations", "url": "/topics/T10417", "kind": "topic-directory", "aeo_cohort": "topic-directory", "provider": "openalex", "revision": "1dfc93fb4a071211", "catalogue_revision": "f050b5d4780b1289", "numeric_address": "36240181364139306", "address_version": "morton4x16-v1", "coordinates": [ 4, 27, 2740, 10417 ], "answer_status": "Directory metadata; local answer requires separate source review", "truth_status": "Subject descriptor, not a factual answer or a demonstrated knowledge gap" } This cluster of papers focuses on the advancements in lung cancer research, particularly in understanding EGFR and ALK mutations, targeted therapy, resistance mechanisms to tyrosine kinase inhibitors, clinical trials evaluating different treatment regimens, genomic profiling for personalized medicine, and the development of treatment guidelines based on molecular biomarkers. The research also explores the concept of oncogene addiction and its implications for targeted therapies. Directory metadata is not a factual answer or evidence of a global knowledge gap. Source: https://openalex.org/T10417 No owner-reviewed local answer yet.