# Cancer Immunotherapy and Biomarkers { "id": "T10158", "title": "Cancer Immunotherapy and Biomarkers", "url": "/topics/T10158", "kind": "topic-directory", "aeo_cohort": "topic-directory", "provider": "openalex", "revision": "8e61cf212aea90e1", "catalogue_revision": "f050b5d4780b1289", "numeric_address": "36108824083622370", "address_version": "morton4x16-v1", "coordinates": [ 4, 27, 2730, 10158 ], "answer_status": "Directory metadata; local answer requires separate source review", "truth_status": "Subject descriptor, not a factual answer or a demonstrated knowledge gap" } This cluster of papers focuses on the advances in cancer immunotherapy research, particularly in the context of immune checkpoint blockade targeting PD-1 and PD-L1, the impact of tumor microenvironment, biomarkers for immunotherapy response, T-cell exhaustion, neoantigens, tumor mutational burden, immune-related adverse events, and the exploration of combination therapies. The research also delves into the intricate mechanisms of cancer immunoediting. Directory metadata is not a factual answer or evidence of a global knowledge gap. Source: https://openalex.org/T10158 No owner-reviewed local answer yet.