# T-cell and B-cell Immunology { "id": "T10031", "title": "T-cell and B-cell Immunology", "url": "/topics/T10031", "kind": "topic-directory", "aeo_cohort": "topic-directory", "provider": "openalex", "revision": "23ee64c1e39eee9d", "catalogue_revision": "f050b5d4780b1289", "numeric_address": "36108563231451341", "address_version": "morton4x16-v1", "coordinates": [ 1, 24, 2403, 10031 ], "answer_status": "Directory metadata; local answer requires separate source review", "truth_status": "Subject descriptor, not a factual answer or a demonstrated knowledge gap" } This cluster of papers focuses on the development, function, and regulation of regulatory T cells (Tregs), particularly emphasizing the role of transcription factor Foxp3, TGF-ß induction, immune tolerance, thymic selection, memory T cells, IL-2 signaling, and their involvement in tumor immunity and immunological surveillance. The cluster also explores the implications of Tregs in autoimmunity and their potential for therapeutic interventions. Directory metadata is not a factual answer or evidence of a global knowledge gap. Source: https://openalex.org/T10031 No owner-reviewed local answer yet.