{"cited_by_count":59943,"description":"This cluster of papers explores the role of triggering receptor expressed on myeloid cells-1 (TREM-1) and endocan in inflammatory responses, sepsis, and various inflammatory diseases. It investigates their impact on immune cells such as macrophages and neutrophils, as well as their potential as diagnostic markers for conditions like pneumonia and septic shock.","display_name":"Inflammation biomarkers and pathways","domain_id":"1","external_ids":{"openalex":"https://openalex.org/T14165","wikipedia":"https://en.wikipedia.org/wiki/Triggering_receptor_expressed_on_myeloid_cells-1"},"field_id":"24","id":"T14165","keywords":[{"display_name":"TREM-1","id":"trem-1","score":0.2813,"url":"https://openalex.org/keywords/trem-1"},{"display_name":"soluble TREM-1","id":"soluble-trem-1","score":0.3684,"url":"https://openalex.org/keywords/soluble-trem-1"}],"legacy_keywords":["TREM-1","Endocan","Inflammation","Sepsis","Macrophages","Neutrophils","Endothelial Cells","Immune Response","Diagnostic Marker","Inflammatory Diseases"],"openalex_id":"https://openalex.org/T14165","source_created_date":"2024-01-23T15:27:21","source_updated_date":"2026-10-17T03:02:00","subfield_id":"2403","url":"/topics/T14165","works_api_url":"https://api.openalex.org/works?filter=topics.id:T14165","works_count":4150,"label":"Inflammation biomarkers and pathways","provider":"openalex","revision":"5e60aeabf598561b","taxonomy_revision":"f050b5d4780b1289","title":"Inflammation biomarkers and pathways","kind":"topic-directory","aeo_cohort":"topic-directory","catalogue_revision":"f050b5d4780b1289","numeric_address":"38360363171457101","address_version":"morton4x16-v1","coordinates":[1,24,2403,14165],"answer_status":"Directory metadata; local answer requires separate source review","truth_status":"Subject descriptor, not a factual answer or a demonstrated knowledge gap","reviewed_answer":null}