{"cited_by_count":74571,"description":"This cluster of papers focuses on the clinical pharmacology, therapeutic significance, and metabolic effects of Policosanol, a new lipid-lowering agent, particularly in the context of hypercholesterolemia and combined hyperlipidemia. It also explores the phytochemical and pharmacological properties of Perilla frutescens, as well as the nutritional significance and antioxidant activity of non-centrifugal sugar.","display_name":"Natural Products and Biological Research","domain_id":"4","external_ids":{"openalex":"https://openalex.org/T13828","wikipedia":"https://en.wikipedia.org/wiki/Policosanol"},"field_id":"27","id":"T13828","keywords":[{"display_name":"simvastatin comparison","id":"simvastatin-comparison","score":0.5269,"url":"https://openalex.org/keywords/simvastatin-comparison"},{"display_name":"statin alternatives","id":"statin-alternatives","score":0.2455,"url":"https://openalex.org/keywords/statin-alternatives"},{"display_name":"atorvastatin comparison","id":"atorvastatin-comparison","score":0.4919,"url":"https://openalex.org/keywords/atorvastatin-comparison"},{"display_name":"Triton X-100-induced hyperlipidemia","id":"triton-x-100-induced-hyperlipidemia","score":0.6178,"url":"https://openalex.org/keywords/triton-x-100-induced-hyperlipidemia"},{"display_name":"Triton-induced hyperlipidemia","id":"triton-induced-hyperlipidemia","score":0.4356,"url":"https://openalex.org/keywords/triton-induced-hyperlipidemia"},{"display_name":"high-fat diet-induced hyperlipidemia","id":"high-fat-diet-induced-hyperlipidemia","score":0.2854,"url":"https://openalex.org/keywords/high-fat-diet-induced-hyperlipidemia"},{"display_name":"blood cholesterol reduction","id":"blood-cholesterol-reduction","score":0.2889,"url":"https://openalex.org/keywords/blood-cholesterol-reduction"},{"display_name":"Triton WR-1339-induced hyperlipidemia","id":"triton-wr-1339-induced-hyperlipidemia","score":0.3486,"url":"https://openalex.org/keywords/triton-wr-1339-induced-hyperlipidemia"},{"display_name":"total cholesterol reduction","id":"total-cholesterol-reduction","score":0.2727,"url":"https://openalex.org/keywords/total-cholesterol-reduction"},{"display_name":"anti-hypercholesterolemia","id":"anti-hypercholesterolemia","score":0.3163,"url":"https://openalex.org/keywords/anti-hypercholesterolemia"}],"legacy_keywords":["Policosanol","Hypercholesterolemia","Perilla frutescens","Lipid-lowering","Nutritional significance","AMP-Kinase activation","Phytochemical profile","Anti-inflammatory effects","Antioxidant activity","Non-centrifugal sugar"],"openalex_id":"https://openalex.org/T13828","source_created_date":"2024-01-23T15:27:20","source_updated_date":"2026-10-17T03:02:00","subfield_id":"2746","url":"/topics/T13828","works_api_url":"https://api.openalex.org/works?filter=topics.id:T13828","works_count":12338,"label":"Natural Products and Biological Research","provider":"openalex","revision":"3ef006266e30004c","taxonomy_revision":"f050b5d4780b1289","title":"Natural Products and Biological Research","kind":"topic-directory","aeo_cohort":"topic-directory","catalogue_revision":"f050b5d4780b1289","numeric_address":"38360587381926242","address_version":"morton4x16-v1","coordinates":[4,27,2746,13828],"answer_status":"Directory metadata; local answer requires separate source review","truth_status":"Subject descriptor, not a factual answer or a demonstrated knowledge gap","reviewed_answer":null}