{"cited_by_count":348146,"description":"This cluster of papers focuses on the investigation of neuroprotective agents such as Citicoline and Cerebrolysin in the context of oxidative stress, ischemic stroke, brain injury, glaucoma, and neurodegenerative diseases like Alzheimer's. The research explores their mechanisms of action, effects on mitochondrial dysfunction, neuroprotection, and potential for promoting neuroregeneration.","display_name":"Neurological Disorders and Treatments","domain_id":"1","external_ids":{"openalex":"https://openalex.org/T13796","wikipedia":"https://en.wikipedia.org/wiki/Neuroprotective_agent"},"field_id":"28","id":"T13796","keywords":[{"display_name":"cerebral ischemia-reperfusion injury","id":"cerebral-ischemia-reperfusion-injury","score":0.2289,"url":"https://openalex.org/keywords/cerebral-ischemia-reperfusion-injury"},{"display_name":"citicoline","id":"citicoline","score":0.4508,"url":"https://openalex.org/keywords/citicoline"},{"display_name":"focal cerebral ischemia-reperfusion injury","id":"focal-cerebral-ischemia-reperfusion-injury","score":0.328,"url":"https://openalex.org/keywords/focal-cerebral-ischemia-reperfusion-injury"},{"display_name":"cerebral infarct volume","id":"cerebral-infarct-volume","score":0.2247,"url":"https://openalex.org/keywords/cerebral-infarct-volume"},{"display_name":"Cerebrolysin","id":"cerebrolysin","score":0.2172,"url":"https://openalex.org/keywords/cerebrolysin"},{"display_name":"CDP-choline","id":"cdp-choline","score":0.2278,"url":"https://openalex.org/keywords/cdp-choline"},{"display_name":"oxiracetam","id":"oxiracetam","score":0.22,"url":"https://openalex.org/keywords/oxiracetam"},{"display_name":"cerebral infarction volume","id":"cerebral-infarction-volume","score":0.2005,"url":"https://openalex.org/keywords/cerebral-infarction-volume"},{"display_name":"cortexin","id":"cortexin","score":0.2303,"url":"https://openalex.org/keywords/cortexin"},{"display_name":"choline alfoscerate","id":"choline-alfoscerate","score":0.2865,"url":"https://openalex.org/keywords/choline-alfoscerate"},{"display_name":"global cerebral ischemia-reperfusion injury","id":"global-cerebral-ischemia-reperfusion-injury","score":0.2081,"url":"https://openalex.org/keywords/global-cerebral-ischemia-reperfusion-injury"},{"display_name":"noopept","id":"noopept","score":0.2373,"url":"https://openalex.org/keywords/noopept"},{"display_name":"NXY-059","id":"nxy-059","score":0.2406,"url":"https://openalex.org/keywords/nxy-059"},{"display_name":"pyritinol","id":"pyritinol","score":0.2062,"url":"https://openalex.org/keywords/pyritinol"},{"display_name":"choline alphoscerate","id":"choline-alphoscerate","score":0.3306,"url":"https://openalex.org/keywords/choline-alphoscerate"},{"display_name":"racetams","id":"racetams","score":0.2755,"url":"https://openalex.org/keywords/racetams"},{"display_name":"nootropic therapy","id":"nootropic-therapy","score":0.2045,"url":"https://openalex.org/keywords/nootropic-therapy"},{"display_name":"in vitro ischemia model","id":"in-vitro-ischemia-model","score":0.2048,"url":"https://openalex.org/keywords/in-vitro-ischemia-model"},{"display_name":"post-ischemic treatment","id":"post-ischemic-treatment","score":0.2446,"url":"https://openalex.org/keywords/post-ischemic-treatment"},{"display_name":"L-alpha-glycerylphosphorylcholine","id":"l-alpha-glycerylphosphorylcholine","score":0.2014,"url":"https://openalex.org/keywords/l-alpha-glycerylphosphorylcholine"}],"legacy_keywords":["Citicoline","Cerebrolysin","Oxidative Stress","Ischemic Stroke","Neuroprotection","Mitochondrial Dysfunction","Glaucoma","Alzheimer's Disease","Retinal Ganglion Cells","Neuroregeneration"],"openalex_id":"https://openalex.org/T13796","source_created_date":"2024-01-23T15:27:19","source_updated_date":"2026-10-17T03:02:00","subfield_id":"2808","url":"/topics/T13796","works_api_url":"https://api.openalex.org/works?filter=topics.id:T13796","works_count":26169,"label":"Neurological Disorders and Treatments","provider":"openalex","revision":"6e5a050c233dd5a7","taxonomy_revision":"f050b5d4780b1289","title":"Neurological Disorders and Treatments","kind":"topic-directory","aeo_cohort":"topic-directory","catalogue_revision":"f050b5d4780b1289","numeric_address":"38360074343049729","address_version":"morton4x16-v1","coordinates":[1,28,2808,13796],"answer_status":"Directory metadata; local answer requires separate source review","truth_status":"Subject descriptor, not a factual answer or a demonstrated knowledge gap","reviewed_answer":null}