{"cited_by_count":76185,"description":"This cluster of papers explores the role of apelin, a novel adipokine, and its receptor APJ in various physiological processes such as cardiovascular regulation, angiogenesis, obesity, diabetes, and neuroprotection. The research covers molecular properties, tissue distribution, signaling pathways, therapeutic potential, and pathophysiological implications of the apelin/APJ system.","display_name":"Apelin-related biomedical research","domain_id":"4","external_ids":{"openalex":"https://openalex.org/T13505","wikipedia":"https://en.wikipedia.org/wiki/Apelin"},"field_id":"27","id":"T13505","keywords":[{"display_name":"apelin","id":"apelin","score":0.5985,"url":"https://openalex.org/keywords/apelin"},{"display_name":"APJ receptor","id":"apj-receptor","score":0.8569,"url":"https://openalex.org/keywords/apj-receptor"},{"display_name":"apelin-13","id":"apelin-13","score":0.8105,"url":"https://openalex.org/keywords/apelin-13"},{"display_name":"apelin receptor","id":"apelin-receptor","score":0.6106,"url":"https://openalex.org/keywords/apelin-receptor"},{"display_name":"Elabela","id":"elabela","score":0.4422,"url":"https://openalex.org/keywords/elabela"},{"display_name":"apelin-12","id":"apelin-12","score":0.803,"url":"https://openalex.org/keywords/apelin-12"},{"display_name":"apelin-36","id":"apelin-36","score":0.7731,"url":"https://openalex.org/keywords/apelin-36"},{"display_name":"apelinergic system","id":"apelinergic-system","score":0.8175,"url":"https://openalex.org/keywords/apelinergic-system"},{"display_name":"apelin signaling","id":"apelin-signaling","score":0.2324,"url":"https://openalex.org/keywords/apelin-signaling"},{"display_name":"APELA","id":"apela","score":0.2945,"url":"https://openalex.org/keywords/apela"}],"legacy_keywords":["Apelin","APJ Receptor","Cardiovascular","Angiogenesis","Obesity","Diabetes","Hypertension","Neuroprotective","Adipokine","G Protein-Coupled Receptor"],"openalex_id":"https://openalex.org/T13505","source_created_date":"2024-01-23T15:27:18","source_updated_date":"2026-10-17T03:02:00","subfield_id":"2736","url":"/topics/T13505","works_api_url":"https://api.openalex.org/works?filter=topics.id:T13505","works_count":3860,"label":"Apelin-related biomedical research","provider":"openalex","revision":"75d2589b085b7935","taxonomy_revision":"f050b5d4780b1289","title":"Apelin-related biomedical research","kind":"topic-directory","aeo_cohort":"topic-directory","catalogue_revision":"f050b5d4780b1289","numeric_address":"38360039907795242","address_version":"morton4x16-v1","coordinates":[4,27,2736,13505],"answer_status":"Directory metadata; local answer requires separate source review","truth_status":"Subject descriptor, not a factual answer or a demonstrated knowledge gap","reviewed_answer":null}