{"cited_by_count":31853,"description":"This cluster of papers explores the effects of chronic systemic exposure to D-galactose on aging, neurodegeneration, oxidative damage, and cognitive impairment in animal models. The protective effects of various natural compounds, including R-a-lipoic acid, ursolic acid, melatonin, and troxerutin, are also investigated. The role of Portulaca oleracea (purslane) in ameliorating the detrimental effects of D-galactose is a recurring theme in the research.","display_name":"Antioxidants, Aging, Portulaca oleracea","domain_id":"1","external_ids":{"openalex":"https://openalex.org/T13446","wikipedia":"https://en.wikipedia.org/wiki/D-Galactose"},"field_id":"28","id":"T13446","keywords":[{"display_name":"D-galactose-induced aging","id":"d-galactose-induced-aging","score":0.3927,"url":"https://openalex.org/keywords/d-galactose-induced-aging"}],"legacy_keywords":["D-Galactose","Aging","Neurodegeneration","Oxidative Stress","Memory Impairment","Antioxidant","Portulaca Oleracea","Cognitive Dysfunction","Neuroprotective Effects","Inflammation"],"openalex_id":"https://openalex.org/T13446","source_created_date":"2024-01-23T15:27:18","source_updated_date":"2026-10-17T03:02:00","subfield_id":"2804","url":"/topics/T13446","works_api_url":"https://api.openalex.org/works?filter=topics.id:T13446","works_count":2776,"label":"Antioxidants, Aging, Portulaca oleracea","provider":"openalex","revision":"41898b41d3be73ad","taxonomy_revision":"f050b5d4780b1289","title":"Antioxidants, Aging, Portulaca oleracea","kind":"topic-directory","aeo_cohort":"topic-directory","catalogue_revision":"f050b5d4780b1289","numeric_address":"38360039840689793","address_version":"morton4x16-v1","coordinates":[1,28,2804,13446],"answer_status":"Directory metadata; local answer requires separate source review","truth_status":"Subject descriptor, not a factual answer or a demonstrated knowledge gap","reviewed_answer":null}