{"cited_by_count":143217,"description":"This cluster of papers explores the impact of resting heart rate on cardiovascular health, focusing on its association with various conditions such as coronary artery disease, heart failure, hypertension, and diabetes mellitus. The papers also investigate the use of Ivabradine, a selective If inhibitor, in managing stable angina and chronic heart failure by reducing heart rate. Additionally, they highlight the predictive value of resting heart rate for mortality and its role as a risk factor for cardiovascular diseases.","display_name":"Heart rate and cardiovascular health","domain_id":"4","external_ids":{"openalex":"https://openalex.org/T13381","wikipedia":"https://en.wikipedia.org/wiki/Resting_heart_rate"},"field_id":"27","id":"T13381","keywords":[{"display_name":"ivabradine","id":"ivabradine","score":0.4075,"url":"https://openalex.org/keywords/ivabradine"},{"display_name":"heart rate reduction","id":"heart-rate-reduction","score":0.2828,"url":"https://openalex.org/keywords/heart-rate-reduction"},{"display_name":"antianginal drugs","id":"antianginal-drugs","score":0.3978,"url":"https://openalex.org/keywords/antianginal-drugs"},{"display_name":"antianginal therapy","id":"antianginal-therapy","score":0.5228,"url":"https://openalex.org/keywords/antianginal-therapy"},{"display_name":"antianginal effect","id":"antianginal-effect","score":0.6066,"url":"https://openalex.org/keywords/antianginal-effect"},{"display_name":"exercise-induced angina","id":"exercise-induced-angina","score":0.3426,"url":"https://openalex.org/keywords/exercise-induced-angina"},{"display_name":"nitroglycerin consumption","id":"nitroglycerin-consumption","score":0.6317,"url":"https://openalex.org/keywords/nitroglycerin-consumption"},{"display_name":"angina treatment","id":"angina-treatment","score":0.5137,"url":"https://openalex.org/keywords/angina-treatment"},{"display_name":"anti-ischemic effect","id":"anti-ischemic-effect","score":0.2485,"url":"https://openalex.org/keywords/anti-ischemic-effect"},{"display_name":"angina frequency","id":"angina-frequency","score":0.3654,"url":"https://openalex.org/keywords/angina-frequency"},{"display_name":"SHIFT trial","id":"shift-trial","score":0.6371,"url":"https://openalex.org/keywords/shift-trial"},{"display_name":"long-acting nitrates","id":"long-acting-nitrates","score":0.3378,"url":"https://openalex.org/keywords/long-acting-nitrates"},{"display_name":"angina management","id":"angina-management","score":0.3616,"url":"https://openalex.org/keywords/angina-management"},{"display_name":"anginal attacks","id":"anginal-attacks","score":0.5711,"url":"https://openalex.org/keywords/anginal-attacks"},{"display_name":"anti-ischemic therapy","id":"anti-ischemic-therapy","score":0.2002,"url":"https://openalex.org/keywords/anti-ischemic-therapy"},{"display_name":"perhexiline maleate","id":"perhexiline-maleate","score":0.2731,"url":"https://openalex.org/keywords/perhexiline-maleate"},{"display_name":"beta-blocker intolerance","id":"beta-blocker-intolerance","score":0.3201,"url":"https://openalex.org/keywords/beta-blocker-intolerance"},{"display_name":"angina pectoris treatment","id":"angina-pectoris-treatment","score":0.5256,"url":"https://openalex.org/keywords/angina-pectoris-treatment"},{"display_name":"nitroglycerin use","id":"nitroglycerin-use","score":0.3428,"url":"https://openalex.org/keywords/nitroglycerin-use"},{"display_name":"angina attack frequency","id":"angina-attack-frequency","score":0.369,"url":"https://openalex.org/keywords/angina-attack-frequency"},{"display_name":"chronic coronary insufficiency","id":"chronic-coronary-insufficiency","score":0.2052,"url":"https://openalex.org/keywords/chronic-coronary-insufficiency"},{"display_name":"angina prevention","id":"angina-prevention","score":0.5415,"url":"https://openalex.org/keywords/angina-prevention"},{"display_name":"nocturnal angina","id":"nocturnal-angina","score":0.3126,"url":"https://openalex.org/keywords/nocturnal-angina"},{"display_name":"angina therapy","id":"angina-therapy","score":0.477,"url":"https://openalex.org/keywords/angina-therapy"},{"display_name":"anti-anginal agents","id":"anti-anginal-agents","score":0.3585,"url":"https://openalex.org/keywords/anti-anginal-agents"}],"legacy_keywords":["Resting Heart Rate","Cardiovascular Disease","Ivabradine","Coronary Artery Disease","Risk Factor","Heart Failure","Mortality","Angina Pectoris","Hypertension","Diabetes Mellitus"],"openalex_id":"https://openalex.org/T13381","source_created_date":"2024-01-23T15:27:18","source_updated_date":"2026-10-17T03:02:00","subfield_id":"2705","url":"/topics/T13381","works_api_url":"https://api.openalex.org/works?filter=topics.id:T13381","works_count":17031,"label":"Heart rate and cardiovascular health","provider":"openalex","revision":"4b5766ca9529ad82","taxonomy_revision":"f050b5d4780b1289","title":"Heart rate and cardiovascular health","kind":"topic-directory","aeo_cohort":"topic-directory","catalogue_revision":"f050b5d4780b1289","numeric_address":"38360037756119342","address_version":"morton4x16-v1","coordinates":[4,27,2705,13381],"answer_status":"Directory metadata; local answer requires separate source review","truth_status":"Subject descriptor, not a factual answer or a demonstrated knowledge gap","reviewed_answer":null}