{"cited_by_count":79757,"description":"This cluster of papers focuses on the treatment, pathogenesis, and epidemiology of Dupuytren's disease, including the use of Collagenase Clostridium Histolyticum, fasciectomy, needle fasciotomy, and radiotherapy. It also explores genetic susceptibility, Wnt signaling, myofibroblasts, TGF-\u00df1 stimulation, and contracture recurrence.","display_name":"Dupuytren's Contracture and Treatments","domain_id":"4","external_ids":{"openalex":"https://openalex.org/T13313","wikipedia":"https://en.wikipedia.org/wiki/Dupuytren%27s_contracture"},"field_id":"27","id":"T13313","keywords":[{"display_name":"Dupuytren's contracture","id":"dupuytren-s-contracture","score":0.8192,"url":"https://openalex.org/keywords/dupuytren-s-contracture"},{"display_name":"Peyronie's disease","id":"peyronie-s-disease","score":0.2145,"url":"https://openalex.org/keywords/peyronie-s-disease"},{"display_name":"collagenase clostridium histolyticum","id":"collagenase-clostridium-histolyticum","score":0.5361,"url":"https://openalex.org/keywords/collagenase-clostridium-histolyticum"},{"display_name":"palmar fascia","id":"palmar-fascia","score":0.8726,"url":"https://openalex.org/keywords/palmar-fascia"},{"display_name":"fasciectomy","id":"fasciectomy","score":0.7453,"url":"https://openalex.org/keywords/fasciectomy"},{"display_name":"hand contracture","id":"hand-contracture","score":0.5252,"url":"https://openalex.org/keywords/hand-contracture"},{"display_name":"collagenase injection","id":"collagenase-injection","score":0.6121,"url":"https://openalex.org/keywords/collagenase-injection"},{"display_name":"palmar aponeurosis","id":"palmar-aponeurosis","score":0.5355,"url":"https://openalex.org/keywords/palmar-aponeurosis"},{"display_name":"percutaneous needle fasciotomy","id":"percutaneous-needle-fasciotomy","score":0.906,"url":"https://openalex.org/keywords/percutaneous-needle-fasciotomy"},{"display_name":"finger contracture","id":"finger-contracture","score":0.3177,"url":"https://openalex.org/keywords/finger-contracture"},{"display_name":"limited fasciectomy","id":"limited-fasciectomy","score":0.9735,"url":"https://openalex.org/keywords/limited-fasciectomy"},{"display_name":"plantar fibromatosis","id":"plantar-fibromatosis","score":0.3477,"url":"https://openalex.org/keywords/plantar-fibromatosis"},{"display_name":"fibroproliferative disorders","id":"fibroproliferative-disease","score":0.2675,"url":"https://openalex.org/keywords/fibroproliferative-disease"},{"display_name":"collagenase clostridium histolyticum injection","id":"collagenase-clostridium-histolyticum-injection","score":0.8206,"url":"https://openalex.org/keywords/collagenase-clostridium-histolyticum-injection"},{"display_name":"Ledderhose disease","id":"ledderhose-disease","score":0.5404,"url":"https://openalex.org/keywords/ledderhose-disease"},{"display_name":"needle aponeurotomy","id":"needle-aponeurotomy","score":0.8843,"url":"https://openalex.org/keywords/needle-aponeurotomy"},{"display_name":"needle fasciotomy","id":"needle-fasciotomy","score":0.8994,"url":"https://openalex.org/keywords/needle-fasciotomy"},{"display_name":"dermofasciectomy","id":"dermofasciectomy","score":0.9172,"url":"https://openalex.org/keywords/dermofasciectomy"},{"display_name":"Dupuytren's nodules","id":"dupuytren-s-nodules","score":0.9504,"url":"https://openalex.org/keywords/dupuytren-s-nodules"},{"display_name":"penile plaque","id":"penile-plaque","score":0.2846,"url":"https://openalex.org/keywords/penile-plaque"},{"display_name":"proximal interphalangeal joint contracture","id":"proximal-interphalangeal-joint-contracture","score":0.6582,"url":"https://openalex.org/keywords/proximal-interphalangeal-joint-contracture"},{"display_name":"tunica albuginea fibrosis","id":"tunica-albuginea-fibrosis","score":0.4049,"url":"https://openalex.org/keywords/tunica-albuginea-fibrosis"},{"display_name":"partial fasciectomy","id":"partial-fasciectomy","score":0.9319,"url":"https://openalex.org/keywords/partial-fasciectomy"},{"display_name":"Dupuytren's cords","id":"dupuytren-s-cords","score":0.9994,"url":"https://openalex.org/keywords/dupuytren-s-cords"},{"display_name":"metacarpophalangeal joint contracture","id":"metacarpophalangeal-joint-contracture","score":0.7692,"url":"https://openalex.org/keywords/metacarpophalangeal-joint-contracture"}],"legacy_keywords":["Collagenase Clostridium Histolyticum","Fasciectomy","Needle Fasciotomy","Wnt Signaling","Epidemiology","Genetic Susceptibility","Radiotherapy","Myofibroblasts","TGF-\u00df1 Stimulation","Contracture Recurrence"],"openalex_id":"https://openalex.org/T13313","source_created_date":"2024-01-23T15:27:17","source_updated_date":"2026-10-17T03:02:00","subfield_id":"2745","url":"/topics/T13313","works_api_url":"https://api.openalex.org/works?filter=topics.id:T13313","works_count":8114,"label":"Dupuytren's Contracture and 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