{"cited_by_count":135127,"description":"This cluster of papers focuses on the use of silymarin, a flavonolignan complex derived from milk thistle, in the treatment of liver diseases, including hepatitis and hepatocellular carcinoma. It explores silymarin's hepatoprotective and antioxidant effects, its potential as a supportive treatment in liver diseases, its role in cancer treatment and chemoprevention, as well as its pharmacokinetics and toxicity.","display_name":"Silymarin and Mushroom Poisoning","domain_id":"4","external_ids":{"openalex":"https://openalex.org/T12689","wikipedia":"https://en.wikipedia.org/wiki/Silymarin"},"field_id":"27","id":"T12689","keywords":[{"display_name":"mushroom poisoning","id":"mushroom-poisoning","score":0.6888,"url":"https://openalex.org/keywords/mushroom-poisoning"},{"display_name":"silymarin","id":"silymarin","score":0.2841,"url":"https://openalex.org/keywords/silymarin"},{"display_name":"Silybum marianum","id":"milk-thistle","score":0.3394,"url":"https://openalex.org/keywords/milk-thistle"},{"display_name":"silibinin","id":"silibinin","score":0.4581,"url":"https://openalex.org/keywords/silibinin"},{"display_name":"poisonous mushrooms","id":"poisonous-mushrooms","score":0.3704,"url":"https://openalex.org/keywords/poisonous-mushrooms"},{"display_name":"Amanita phalloides","id":"amanita-phalloides","score":0.5696,"url":"https://openalex.org/keywords/amanita-phalloides"},{"display_name":"flavonolignans","id":"flavonolignans","score":0.4959,"url":"https://openalex.org/keywords/flavonolignans"},{"display_name":"amatoxins","id":"amatoxins","score":0.5649,"url":"https://openalex.org/keywords/amatoxins"},{"display_name":"mushroom toxins","id":"mushroom-toxins","score":0.3331,"url":"https://openalex.org/keywords/mushroom-toxins"},{"display_name":"Amanita phalloides poisoning","id":"amanita-phalloides-poisoning","score":0.8167,"url":"https://openalex.org/keywords/amanita-phalloides-poisoning"},{"display_name":"poisonous fungi","id":"toxic-fungi","score":0.215,"url":"https://openalex.org/keywords/toxic-fungi"},{"display_name":"silychristin","id":"silychristin","score":0.5456,"url":"https://openalex.org/keywords/silychristin"},{"display_name":"death cap mushroom","id":"death-cap-mushroom","score":0.4562,"url":"https://openalex.org/keywords/death-cap-mushroom"},{"display_name":"silydianin","id":"silydianin","score":0.5576,"url":"https://openalex.org/keywords/silydianin"},{"display_name":"mushroom toxicity","id":"mushroom-toxicity","score":0.4316,"url":"https://openalex.org/keywords/mushroom-toxicity"},{"display_name":"mushroom consumption","id":"mushroom-consumption","score":0.2074,"url":"https://openalex.org/keywords/mushroom-consumption"},{"display_name":"fungal poisoning","id":"fungal-poisoning","score":0.6077,"url":"https://openalex.org/keywords/fungal-poisoning"},{"display_name":"silybin A","id":"silybin-a","score":0.6106,"url":"https://openalex.org/keywords/silybin-a"},{"display_name":"silybin B","id":"silybin-b","score":0.5992,"url":"https://openalex.org/keywords/silybin-b"},{"display_name":"amatoxin poisoning","id":"amatoxin-poisoning","score":0.9259,"url":"https://openalex.org/keywords/amatoxin-poisoning"},{"display_name":"milk thistle seeds","id":"milk-thistle-seeds","score":0.3698,"url":"https://openalex.org/keywords/milk-thistle-seeds"},{"display_name":"phallotoxins","id":"phallotoxins","score":0.3272,"url":"https://openalex.org/keywords/phallotoxins"},{"display_name":"amanitin","id":"amanitin","score":0.254,"url":"https://openalex.org/keywords/amanitin"},{"display_name":"Amanita virosa","id":"amanita-virosa","score":0.3569,"url":"https://openalex.org/keywords/amanita-virosa"},{"display_name":"isosilybin","id":"isosilybin","score":0.4599,"url":"https://openalex.org/keywords/isosilybin"}],"legacy_keywords":["Silymarin","Liver Diseases","Hepatoprotective","Antioxidant","Cancer Treatment","Pharmacokinetics","Milk Thistle","Hepatitis C","Chemoprevention","Toxicity"],"openalex_id":"https://openalex.org/T12689","source_created_date":"2024-01-23T15:27:15","source_updated_date":"2026-10-17T03:02:00","subfield_id":"2740","url":"/topics/T12689","works_api_url":"https://api.openalex.org/works?filter=topics.id:T12689","works_count":10707,"label":"Silymarin and Mushroom Poisoning","provider":"openalex","revision":"5b900e5acc3dd714","taxonomy_revision":"f050b5d4780b1289","title":"Silymarin and Mushroom Poisoning","kind":"topic-directory","aeo_cohort":"topic-directory","catalogue_revision":"f050b5d4780b1289","numeric_address":"38351278040818986","address_version":"morton4x16-v1","coordinates":[4,27,2740,12689],"answer_status":"Directory metadata; local answer requires separate source review","truth_status":"Subject descriptor, not a factual answer or a demonstrated knowledge gap","reviewed_answer":null}