{"cited_by_count":260994,"description":"This cluster of papers explores the impact of chronic stress, neuroendocrine modulation, anesthetic techniques, and immune suppression on tumor growth, metastasis promotion, and angiogenesis regulation. It delves into the influence of the nervous system during the perioperative period and highlights the role of adrenergic signaling in cancer progression.","display_name":"Cancer, Stress, Anesthesia, and Immune Response","domain_id":"4","external_ids":{"openalex":"https://openalex.org/T12626","wikipedia":"https://en.wikipedia.org/wiki/Chronic_stress_and_cancer"},"field_id":"27","id":"T12626","keywords":[{"display_name":"postoperative immunosuppression","id":"postoperative-immunosuppression","score":0.4185,"url":"https://openalex.org/keywords/postoperative-immunosuppression"},{"display_name":"tumor innervation","id":"tumor-innervation","score":0.545,"url":"https://openalex.org/keywords/tumor-innervation"},{"display_name":"perioperative immunosuppression","id":"perioperative-immunosuppression","score":0.462,"url":"https://openalex.org/keywords/perioperative-immunosuppression"},{"display_name":"psychological factors in cancer","id":"psychological-factors-in-cancer","score":0.2755,"url":"https://openalex.org/keywords/psychological-factors-in-cancer"},{"display_name":"postoperative immune response","id":"postoperative-immune-response","score":0.2525,"url":"https://openalex.org/keywords/postoperative-immune-response"},{"display_name":"cancer neuroscience","id":"cancer-neuroscience","score":0.4566,"url":"https://openalex.org/keywords/cancer-neuroscience"},{"display_name":"postoperative immune function","id":"postoperative-immune-function","score":0.2555,"url":"https://openalex.org/keywords/postoperative-immune-function"},{"display_name":"stress and cancer","id":"stress-and-cancer","score":0.607,"url":"https://openalex.org/keywords/stress-and-cancer"},{"display_name":"perioperative immune function","id":"perioperative-immune-function","score":0.59,"url":"https://openalex.org/keywords/perioperative-immune-function"},{"display_name":"perioperative immune response","id":"perioperative-immune-response","score":0.5388,"url":"https://openalex.org/keywords/perioperative-immune-response"},{"display_name":"perioperative immunomodulation","id":"perioperative-immunomodulation","score":0.5667,"url":"https://openalex.org/keywords/perioperative-immunomodulation"},{"display_name":"psychosocial factors in cancer","id":"psychosocial-factors-in-cancer","score":0.3057,"url":"https://openalex.org/keywords/psychosocial-factors-in-cancer"},{"display_name":"perioperative inflammatory response","id":"perioperative-inflammatory-response","score":0.2283,"url":"https://openalex.org/keywords/perioperative-inflammatory-response"},{"display_name":"volatile anesthesia","id":"volatile-anesthesia","score":0.2248,"url":"https://openalex.org/keywords/volatile-anesthesia"},{"display_name":"postoperative immune recovery","id":"postoperative-immune-recovery","score":0.2584,"url":"https://openalex.org/keywords/postoperative-immune-recovery"}],"legacy_keywords":["Chronic Stress","Tumor Growth","Neuroendocrine Modulation","Anesthetic Technique","Immune Suppression","Metastasis Promotion","Adrenergic Signaling","Nervous System Influence","Angiogenesis Regulation","Perioperative Period"],"openalex_id":"https://openalex.org/T12626","source_created_date":"2024-01-23T15:27:15","source_updated_date":"2026-10-17T03:02:00","subfield_id":"2738","url":"/topics/T12626","works_api_url":"https://api.openalex.org/works?filter=topics.id:T12626","works_count":17143,"label":"Cancer, Stress, Anesthesia, and Immune Response","provider":"openalex","revision":"11f5e254b7d5ede8","taxonomy_revision":"f050b5d4780b1289","title":"Cancer, Stress, Anesthesia, and Immune Response","kind":"topic-directory","aeo_cohort":"topic-directory","catalogue_revision":"f050b5d4780b1289","numeric_address":"38351276027552226","address_version":"morton4x16-v1","coordinates":[4,27,2738,12626],"answer_status":"Directory metadata; local answer requires separate source review","truth_status":"Subject descriptor, not a factual answer or a demonstrated knowledge gap","reviewed_answer":null}