{"cited_by_count":179830,"description":"This cluster of papers focuses on the diagnosis and treatment of patent ductus arteriosus (PDA) in preterm infants, with a particular emphasis on the use of indomethacin prophylaxis and ibuprofen treatment. It also explores the association between PDA and neonatal morbidity, the use of echocardiography for assessment, and the impact of ductal closure on outcomes such as bronchopulmonary dysplasia. Additionally, it examines the relationship between PDA and congenital heart disease, including cardiomyopathy.","display_name":"Cardiovascular Conditions and Treatments","domain_id":"4","external_ids":{"openalex":"https://openalex.org/T12272","wikipedia":"https://en.wikipedia.org/wiki/Patent_ductus_arteriosus"},"field_id":"27","id":"T12272","keywords":[{"display_name":"patent ductus arteriosus","id":"patent-ductus-arteriosus","score":0.4669,"url":"https://openalex.org/keywords/patent-ductus-arteriosus"},{"display_name":"ductus ligation","id":"ductus-arteriosus-ligation","score":0.6777,"url":"https://openalex.org/keywords/ductus-arteriosus-ligation"},{"display_name":"ductus arteriosus","id":"ductus-arteriosus","score":0.4398,"url":"https://openalex.org/keywords/ductus-arteriosus"},{"display_name":"ductus arteriosus closure","id":"ductus-arteriosus-closure","score":0.7215,"url":"https://openalex.org/keywords/ductus-arteriosus-closure"},{"display_name":"surgical ligation","id":"surgical-ligation","score":0.4004,"url":"https://openalex.org/keywords/surgical-ligation"},{"display_name":"PDA closure","id":"pda-closure","score":0.9365,"url":"https://openalex.org/keywords/pda-closure"},{"display_name":"ductal closure","id":"ductal-closure","score":0.8444,"url":"https://openalex.org/keywords/ductal-closure"},{"display_name":"Amplatzer duct occluder","id":"amplatzer-duct-occluder","score":0.5328,"url":"https://openalex.org/keywords/amplatzer-duct-occluder"},{"display_name":"persistent ductus arteriosus","id":"persistent-ductus-arteriosus","score":0.3465,"url":"https://openalex.org/keywords/persistent-ductus-arteriosus"},{"display_name":"hemodynamically significant PDA","id":"hemodynamically-significant-pda","score":0.9849,"url":"https://openalex.org/keywords/hemodynamically-significant-pda"},{"display_name":"hemodynamically significant patent ductus arteriosus","id":"hemodynamically-significant-patent-ductus-arteriosus","score":0.9759,"url":"https://openalex.org/keywords/hemodynamically-significant-patent-ductus-arteriosus"},{"display_name":"ductus arteriosus patency","id":"ductus-arteriosus-patency","score":0.4553,"url":"https://openalex.org/keywords/ductus-arteriosus-patency"},{"display_name":"canine congenital heart disease","id":"canine-congenital-heart-disease","score":0.3087,"url":"https://openalex.org/keywords/canine-congenital-heart-disease"},{"display_name":"ductus arteriosus aneurysm","id":"ductus-arteriosus-aneurysm","score":0.6611,"url":"https://openalex.org/keywords/ductus-arteriosus-aneurysm"},{"display_name":"ductus arteriosus constriction","id":"ductus-arteriosus-constriction","score":0.5299,"url":"https://openalex.org/keywords/ductus-arteriosus-constriction"},{"display_name":"transcatheter PDA closure","id":"transcatheter-pda-closure","score":0.8921,"url":"https://openalex.org/keywords/transcatheter-pda-closure"},{"display_name":"Gianturco coils","id":"gianturco-coils","score":0.3684,"url":"https://openalex.org/keywords/gianturco-coils"},{"display_name":"oral ibuprofen","id":"oral-ibuprofen","score":0.8069,"url":"https://openalex.org/keywords/oral-ibuprofen"},{"display_name":"ductal diameter","id":"ductal-diameter","score":0.7308,"url":"https://openalex.org/keywords/ductal-diameter"},{"display_name":"transcatheter ductus ligation","id":"transcatheter-ductus-ligation","score":0.7752,"url":"https://openalex.org/keywords/transcatheter-ductus-ligation"},{"display_name":"pharmacological closure","id":"pharmacological-closure","score":0.9782,"url":"https://openalex.org/keywords/pharmacological-closure"},{"display_name":"patent ductus arteriosus closure","id":"patent-ductus-arteriosus-closure","score":0.2224,"url":"https://openalex.org/keywords/patent-ductus-arteriosus-closure"},{"display_name":"ductal constriction","id":"ductal-constriction","score":0.7109,"url":"https://openalex.org/keywords/ductal-constriction"},{"display_name":"ductal patency","id":"ductal-patency","score":0.4678,"url":"https://openalex.org/keywords/ductal-patency"},{"display_name":"fetal ductus arteriosus","id":"fetal-ductus-arteriosus","score":0.8068,"url":"https://openalex.org/keywords/fetal-ductus-arteriosus"}],"legacy_keywords":["Patent Ductus Arteriosus","Preterm Infants","Echocardiography","Indomethacin Prophylaxis","Cardiomyopathy","Ibuprofen Treatment","Neonatal Morbidity","Ductal Closure","Congenital Heart Disease","Bronchopulmonary Dysplasia"],"openalex_id":"https://openalex.org/T12272","source_created_date":"2024-01-23T15:27:13","source_updated_date":"2026-10-17T03:02:00","subfield_id":"2741","url":"/topics/T12272","works_api_url":"https://api.openalex.org/works?filter=topics.id:T12272","works_count":16390,"label":"Cardiovascular Conditions and Treatments","provider":"openalex","revision":"2d5dcd01bc184092","taxonomy_revision":"f050b5d4780b1289","title":"Cardiovascular Conditions and Treatments","kind":"topic-directory","aeo_cohort":"topic-directory","catalogue_revision":"f050b5d4780b1289","numeric_address":"36249561706931494","address_version":"morton4x16-v1","coordinates":[4,27,2741,12272],"answer_status":"Directory metadata; local answer requires separate source review","truth_status":"Subject descriptor, not a factual answer or a demonstrated knowledge gap","reviewed_answer":null}