{"cited_by_count":163182,"description":"This cluster of papers focuses on the diagnosis and management of hereditary hemorrhagic telangiectasia (HHT), a genetic disorder characterized by vascular malformations. It covers topics such as genetics, pulmonary arteriovenous malformations, embolization, epistaxis, liver involvement, SMAD4 mutations, and vascular anomalies.","display_name":"Vascular Anomalies and Treatments","domain_id":"4","external_ids":{"openalex":"https://openalex.org/T12199","wikipedia":"https://en.wikipedia.org/wiki/Hereditary_hemorrhagic_telangiectasia"},"field_id":"27","id":"T12199","keywords":[{"display_name":"hereditary hemorrhagic telangiectasia","id":"hereditary-hemorrhagic-telangiectasia","score":0.7165,"url":"https://openalex.org/keywords/hereditary-hemorrhagic-telangiectasia"},{"display_name":"pulmonary arteriovenous malformation","id":"pulmonary-arteriovenous-malformation","score":0.7373,"url":"https://openalex.org/keywords/pulmonary-arteriovenous-malformation"},{"display_name":"bronchial artery embolization","id":"bronchial-artery-embolization","score":0.4179,"url":"https://openalex.org/keywords/bronchial-artery-embolization"},{"display_name":"massive hemoptysis","id":"massive-hemoptysis","score":0.2818,"url":"https://openalex.org/keywords/massive-hemoptysis"},{"display_name":"ALK1","id":"alk1","score":0.2496,"url":"https://openalex.org/keywords/alk1"},{"display_name":"recurrent epistaxis","id":"recurrent-epistaxis","score":0.3839,"url":"https://openalex.org/keywords/recurrent-epistaxis"},{"display_name":"posterior epistaxis","id":"posterior-epistaxis","score":0.5475,"url":"https://openalex.org/keywords/posterior-epistaxis"},{"display_name":"epistaxis management","id":"epistaxis-management","score":0.555,"url":"https://openalex.org/keywords/epistaxis-management"},{"display_name":"nasal telangiectasia","id":"nasal-telangiectasia","score":0.8573,"url":"https://openalex.org/keywords/nasal-telangiectasia"},{"display_name":"recurrent hemoptysis","id":"recurrent-hemoptysis","score":0.2656,"url":"https://openalex.org/keywords/recurrent-hemoptysis"},{"display_name":"hepatic arteriovenous malformations","id":"hepatic-arteriovenous-malformations","score":0.6298,"url":"https://openalex.org/keywords/hepatic-arteriovenous-malformations"},{"display_name":"Cura\u00e7ao criteria","id":"curacao-criteria","score":0.959,"url":"https://openalex.org/keywords/curacao-criteria"},{"display_name":"nasal hemorrhage","id":"nasal-hemorrhage","score":0.2702,"url":"https://openalex.org/keywords/nasal-hemorrhage"},{"display_name":"bronchial artery aneurysm","id":"bronchial-artery-aneurysm","score":0.3224,"url":"https://openalex.org/keywords/bronchial-artery-aneurysm"},{"display_name":"epistaxis treatment","id":"epistaxis-treatment","score":0.4893,"url":"https://openalex.org/keywords/epistaxis-treatment"},{"display_name":"refractory epistaxis","id":"refractory-epistaxis","score":0.5801,"url":"https://openalex.org/keywords/refractory-epistaxis"},{"display_name":"vascular dysplasia","id":"vascular-dysplasia","score":0.4385,"url":"https://openalex.org/keywords/vascular-dysplasia"},{"display_name":"Osler's disease","id":"osler-s-disease","score":0.3859,"url":"https://openalex.org/keywords/osler-s-disease"},{"display_name":"pulmonary vascular malformation","id":"pulmonary-vascular-malformation","score":0.4686,"url":"https://openalex.org/keywords/pulmonary-vascular-malformation"},{"display_name":"bronchial arteriography","id":"bronchial-arteriography","score":0.2893,"url":"https://openalex.org/keywords/bronchial-arteriography"},{"display_name":"intractable epistaxis","id":"intractable-epistaxis","score":0.6474,"url":"https://openalex.org/keywords/intractable-epistaxis"},{"display_name":"anterior epistaxis","id":"anterior-epistaxis","score":0.4976,"url":"https://openalex.org/keywords/anterior-epistaxis"},{"display_name":"embolotherapy","id":"embolotherapy","score":0.2229,"url":"https://openalex.org/keywords/embolotherapy"},{"display_name":"hereditary telangiectasia","id":"hereditary-telangiectasia","score":0.4542,"url":"https://openalex.org/keywords/hereditary-telangiectasia"},{"display_name":"hemoptysis recurrence","id":"hemoptysis-recurrence","score":0.5183,"url":"https://openalex.org/keywords/hemoptysis-recurrence"}],"legacy_keywords":["Hereditary Hemorrhagic Telangiectasia","Diagnosis","Management","Genetics","Pulmonary Arteriovenous Malformations","Embolization","Epistaxis","Liver Involvement","SMAD4 Mutations","Vascular Anomalies"],"openalex_id":"https://openalex.org/T12199","source_created_date":"2024-01-23T15:27:13","source_updated_date":"2026-10-17T03:02:00","subfield_id":"2716","url":"/topics/T12199","works_api_url":"https://api.openalex.org/works?filter=topics.id:T12199","works_count":17236,"label":"Vascular Anomalies and Treatments","provider":"openalex","revision":"41bdac865da3a5b1","taxonomy_revision":"f050b5d4780b1289","title":"Vascular Anomalies and Treatments","kind":"topic-directory","aeo_cohort":"topic-directory","catalogue_revision":"f050b5d4780b1289","numeric_address":"36249561568013738","address_version":"morton4x16-v1","coordinates":[4,27,2716,12199],"answer_status":"Directory metadata; local answer requires separate source review","truth_status":"Subject descriptor, not a factual answer or a demonstrated knowledge gap","reviewed_answer":null}