{"cited_by_count":370485,"description":"This cluster of papers focuses on transition-metal-catalyzed sulfur chemistry, including sulfur bond formation, catalytic coupling reactions, and the synthesis of sulfur-containing compounds. It explores applications in drug design, organic synthesis, thiolation, sulfonylation, and medicinal chemistry.","display_name":"Sulfur-Based Synthesis Techniques","domain_id":"3","external_ids":{"openalex":"https://openalex.org/T12189","wikipedia":"https://en.wikipedia.org/wiki/Sulfur_chemistry"},"field_id":"16","id":"T12189","keywords":[{"display_name":"C\u2013S bond formation","id":"carbon-sulfur-bond-formation","score":0.3612,"url":"https://openalex.org/keywords/carbon-sulfur-bond-formation"},{"display_name":"organosulfur synthesis","id":"organosulfur-synthesis","score":0.2593,"url":"https://openalex.org/keywords/organosulfur-synthesis"},{"display_name":"sulfone synthesis","id":"sulfone-synthesis","score":0.5347,"url":"https://openalex.org/keywords/sulfone-synthesis"},{"display_name":"sulfenylation","id":"sulfenylation","score":0.5079,"url":"https://openalex.org/keywords/sulfenylation"},{"display_name":"sodium sulfinates","id":"sodium-sulfinates","score":0.6546,"url":"https://openalex.org/keywords/sodium-sulfinates"},{"display_name":"sulfonylation","id":"sulfonylation","score":0.3433,"url":"https://openalex.org/keywords/sulfonylation"},{"display_name":"sulfonyl chlorides","id":"sulfonyl-chlorides","score":0.2094,"url":"https://openalex.org/keywords/sulfonyl-chlorides"},{"display_name":"sulfide synthesis","id":"sulfide-synthesis","score":0.34,"url":"https://openalex.org/keywords/sulfide-synthesis"},{"display_name":"C\u2013S cross-coupling","id":"c-s-cross-coupling","score":0.4974,"url":"https://openalex.org/keywords/c-s-cross-coupling"},{"display_name":"thioether synthesis","id":"thioether-synthesis","score":0.278,"url":"https://openalex.org/keywords/thioether-synthesis"},{"display_name":"aryl sulfides","id":"aryl-sulfides","score":0.4086,"url":"https://openalex.org/keywords/aryl-sulfides"},{"display_name":"sulfonyl hydrazides","id":"sulfonyl-hydrazides","score":0.5571,"url":"https://openalex.org/keywords/sulfonyl-hydrazides"},{"display_name":"disulfide synthesis","id":"disulfide-synthesis","score":0.4283,"url":"https://openalex.org/keywords/disulfide-synthesis"},{"display_name":"diaryl sulfides","id":"diaryl-sulfides","score":0.5764,"url":"https://openalex.org/keywords/diaryl-sulfides"},{"display_name":"sulfinic acids","id":"sulfinic-acids","score":0.3343,"url":"https://openalex.org/keywords/sulfinic-acids"},{"display_name":"diaryl disulfides","id":"diaryl-disulfides","score":0.4872,"url":"https://openalex.org/keywords/diaryl-disulfides"},{"display_name":"thiosulfonates","id":"thiosulfonates","score":0.3847,"url":"https://openalex.org/keywords/thiosulfonates"},{"display_name":"sulfinates","id":"sulfinates","score":0.3335,"url":"https://openalex.org/keywords/sulfinates"},{"display_name":"\u03b2-keto sulfones","id":"beta-keto-sulfones","score":0.3555,"url":"https://openalex.org/keywords/beta-keto-sulfones"},{"display_name":"sulfenyl compounds","id":"sulfenyl-compounds","score":0.467,"url":"https://openalex.org/keywords/sulfenyl-compounds"},{"display_name":"sulfenamides","id":"sulfenamides","score":0.2344,"url":"https://openalex.org/keywords/sulfenamides"},{"display_name":"thiol synthesis","id":"thiol-synthesis","score":0.2663,"url":"https://openalex.org/keywords/thiol-synthesis"},{"display_name":"S-arylation","id":"s-arylation","score":0.5571,"url":"https://openalex.org/keywords/s-arylation"},{"display_name":"thiocyanation","id":"thiocyanation","score":0.301,"url":"https://openalex.org/keywords/thiocyanation"},{"display_name":"aryl thiols","id":"aryl-thiols","score":0.3843,"url":"https://openalex.org/keywords/aryl-thiols"}],"legacy_keywords":["Transition-Metal-Catalyzed","Sulfur Bond Formation","Catalytic Coupling Reactions","Sulfur-Containing Compounds","Drug Design","Organic Synthesis","Thiolation","Sulfonylation","Aryl Halides","Medicinal Chemistry"],"openalex_id":"https://openalex.org/T12189","source_created_date":"2024-01-23T15:27:13","source_updated_date":"2026-10-17T03:02:00","subfield_id":"1605","url":"/topics/T12189","works_api_url":"https://api.openalex.org/works?filter=topics.id:T12189","works_count":25542,"label":"Sulfur-Based Synthesis Techniques","provider":"openalex","revision":"f62a4f9627db445c","taxonomy_revision":"f050b5d4780b1289","title":"Sulfur-Based Synthesis Techniques","kind":"topic-directory","aeo_cohort":"topic-directory","catalogue_revision":"f050b5d4780b1289","numeric_address":"36183589855595549","address_version":"morton4x16-v1","coordinates":[3,16,1605,12189],"answer_status":"Directory metadata; local answer requires separate source review","truth_status":"Subject descriptor, not a factual answer or a demonstrated knowledge gap","reviewed_answer":null}