{"cited_by_count":211621,"description":"This cluster of papers explores the pathophysiology, clinical features, and outcomes of stress-induced cardiomyopathy, also known as Takotsubo Syndrome. It delves into the role of neurohumoral features, catecholamine cardiotoxicity, and the brain-heart axis in the development of this condition. Additionally, it investigates the association with neurogenic pulmonary edema, cardiac troponin elevation, myocardial stunning, and its occurrence after subarachnoid hemorrhage.","display_name":"Takotsubo Cardiomyopathy and Associated Phenomena","domain_id":"4","external_ids":{"openalex":"https://openalex.org/T12082","wikipedia":"https://en.wikipedia.org/wiki/Takotsubo_syndrome"},"field_id":"27","id":"T12082","keywords":[{"display_name":"takotsubo cardiomyopathy","id":"takotsubo-cardiomyopathy","score":0.8397,"url":"https://openalex.org/keywords/takotsubo-cardiomyopathy"},{"display_name":"neurogenic pulmonary edema","id":"neurogenic-pulmonary-edema","score":0.4888,"url":"https://openalex.org/keywords/neurogenic-pulmonary-edema"},{"display_name":"left ventricular apical ballooning","id":"left-ventricular-apical-ballooning","score":0.7136,"url":"https://openalex.org/keywords/left-ventricular-apical-ballooning"},{"display_name":"catecholamine surge","id":"catecholamine-surge","score":0.5398,"url":"https://openalex.org/keywords/catecholamine-surge"},{"display_name":"acute coronary syndrome mimic","id":"acute-coronary-syndrome-mimic","score":0.3758,"url":"https://openalex.org/keywords/acute-coronary-syndrome-mimic"},{"display_name":"reverse takotsubo cardiomyopathy","id":"reverse-takotsubo-cardiomyopathy","score":0.9588,"url":"https://openalex.org/keywords/reverse-takotsubo-cardiomyopathy"},{"display_name":"reversible cardiomyopathy","id":"reversible-cardiomyopathy","score":0.2746,"url":"https://openalex.org/keywords/reversible-cardiomyopathy"},{"display_name":"left ventricular wall motion abnormalities","id":"left-ventricular-wall-motion-abnormalities","score":0.2007,"url":"https://openalex.org/keywords/left-ventricular-wall-motion-abnormalities"},{"display_name":"acute myocardial infarction mimic","id":"acute-myocardial-infarction-mimic","score":0.3331,"url":"https://openalex.org/keywords/acute-myocardial-infarction-mimic"},{"display_name":"transient left ventricular dysfunction","id":"transient-left-ventricular-dysfunction","score":0.8062,"url":"https://openalex.org/keywords/transient-left-ventricular-dysfunction"},{"display_name":"myocardial infarction mimic","id":"myocardial-infarction-mimic","score":0.2353,"url":"https://openalex.org/keywords/myocardial-infarction-mimic"},{"display_name":"neurogenic stunned myocardium","id":"neurogenic-stunned-myocardium","score":0.7842,"url":"https://openalex.org/keywords/neurogenic-stunned-myocardium"},{"display_name":"cardiac stress response","id":"cardiac-stress-response","score":0.2118,"url":"https://openalex.org/keywords/cardiac-stress-response"},{"display_name":"catecholamine-induced cardiomyopathy","id":"catecholamine-induced-cardiomyopathy","score":0.3838,"url":"https://openalex.org/keywords/catecholamine-induced-cardiomyopathy"},{"display_name":"recurrent takotsubo cardiomyopathy","id":"recurrent-takotsubo-cardiomyopathy","score":0.9787,"url":"https://openalex.org/keywords/recurrent-takotsubo-cardiomyopathy"},{"display_name":"differential diagnosis of acute coronary syndrome","id":"differential-diagnosis-of-acute-coronary-syndrome","score":0.6117,"url":"https://openalex.org/keywords/differential-diagnosis-of-acute-coronary-syndrome"},{"display_name":"transient left ventricular apical ballooning","id":"transient-left-ventricular-apical-ballooning","score":0.9474,"url":"https://openalex.org/keywords/transient-left-ventricular-apical-ballooning"},{"display_name":"reversible left ventricular dysfunction","id":"reversible-left-ventricular-dysfunction","score":0.5635,"url":"https://openalex.org/keywords/reversible-left-ventricular-dysfunction"},{"display_name":"apical akinesia","id":"apical-akinesia","score":0.6549,"url":"https://openalex.org/keywords/apical-akinesia"},{"display_name":"inverted takotsubo cardiomyopathy","id":"inverted-takotsubo-cardiomyopathy","score":0.9611,"url":"https://openalex.org/keywords/inverted-takotsubo-cardiomyopathy"},{"display_name":"left ventricular akinesia","id":"left-ventricular-akinesia","score":0.5076,"url":"https://openalex.org/keywords/left-ventricular-akinesia"},{"display_name":"apical akinesis","id":"apical-akinesis","score":0.7066,"url":"https://openalex.org/keywords/apical-akinesis"},{"display_name":"catecholamine toxicity","id":"catecholamine-toxicity","score":0.3512,"url":"https://openalex.org/keywords/catecholamine-toxicity"},{"display_name":"left ventricular ballooning","id":"left-ventricular-ballooning","score":0.9229,"url":"https://openalex.org/keywords/left-ventricular-ballooning"},{"display_name":"reversible myocardial dysfunction","id":"reversible-myocardial-dysfunction","score":0.2701,"url":"https://openalex.org/keywords/reversible-myocardial-dysfunction"}],"legacy_keywords":["Stress-Induced Cardiomyopathy","Takotsubo Syndrome","Neurohumoral Features","Apical Ballooning Syndrome","Catecholamine Cardiotoxicity","Neurogenic Pulmonary Edema","Cardiac Troponin Elevation","Brain-Heart Axis","Myocardial Stunning","Subarachnoid Hemorrhage"],"openalex_id":"https://openalex.org/T12082","source_created_date":"2024-01-23T15:27:13","source_updated_date":"2026-10-17T03:02:00","subfield_id":"2705","url":"/topics/T12082","works_api_url":"https://api.openalex.org/works?filter=topics.id:T12082","works_count":21872,"label":"Takotsubo Cardiomyopathy and Associated Phenomena","provider":"openalex","revision":"e936bdc8efc561f3","taxonomy_revision":"f050b5d4780b1289","title":"Takotsubo Cardiomyopathy and Associated Phenomena","kind":"topic-directory","aeo_cohort":"topic-directory","catalogue_revision":"f050b5d4780b1289","numeric_address":"36249559421034918","address_version":"morton4x16-v1","coordinates":[4,27,2705,12082],"answer_status":"Directory metadata; local answer requires separate source review","truth_status":"Subject descriptor, not a factual answer or a demonstrated knowledge gap","reviewed_answer":null}