{"cited_by_count":194535,"description":"This cluster of papers focuses on the therapeutic potential of berberine alkaloids, particularly in the context of metabolic disorders such as diabetes mellitus. The research covers various aspects including the mechanisms of action, anti-inflammatory effects, cholesterol-lowering properties, and potential anticancer activities. Additionally, it explores the traditional use of berberine in Chinese medicine and its impact on glucose metabolism.","display_name":"Berberine and alkaloids research","domain_id":"4","external_ids":{"openalex":"https://openalex.org/T12059","wikipedia":"https://en.wikipedia.org/wiki/Berberine"},"field_id":"27","id":"T12059","keywords":[{"display_name":"berberine","id":"berberine","score":0.3358,"url":"https://openalex.org/keywords/berberine"},{"display_name":"protoberberine alkaloids","id":"protoberberine-alkaloids","score":0.3178,"url":"https://openalex.org/keywords/protoberberine-alkaloids"},{"display_name":"berberine derivatives","id":"berberine-derivatives","score":0.5505,"url":"https://openalex.org/keywords/berberine-derivatives"},{"display_name":"berberine alkaloids","id":"berberine-alkaloids","score":0.4069,"url":"https://openalex.org/keywords/berberine-alkaloids"},{"display_name":"berbamine","id":"berbamine","score":0.272,"url":"https://openalex.org/keywords/berbamine"},{"display_name":"berberine chloride","id":"berberine-chloride","score":0.2499,"url":"https://openalex.org/keywords/berberine-chloride"},{"display_name":"berberrubine","id":"berberrubine","score":0.4437,"url":"https://openalex.org/keywords/berberrubine"},{"display_name":"tetrahydroberberine","id":"tetrahydroberberine","score":0.3911,"url":"https://openalex.org/keywords/tetrahydroberberine"},{"display_name":"dihydroberberine","id":"dihydroberberine","score":0.5481,"url":"https://openalex.org/keywords/dihydroberberine"},{"display_name":"tetrahydroprotoberberines","id":"tetrahydroprotoberberines","score":0.26,"url":"https://openalex.org/keywords/tetrahydroprotoberberines"},{"display_name":"columbamine","id":"columbamine","score":0.2026,"url":"https://openalex.org/keywords/columbamine"},{"display_name":"protoberberines","id":"protoberberines","score":0.2286,"url":"https://openalex.org/keywords/protoberberines"},{"display_name":"tetrahydroprotoberberine alkaloids","id":"tetrahydroprotoberberine-alkaloids","score":0.2664,"url":"https://openalex.org/keywords/tetrahydroprotoberberine-alkaloids"},{"display_name":"berberine sulfate","id":"berberine-sulfate","score":0.2267,"url":"https://openalex.org/keywords/berberine-sulfate"}],"legacy_keywords":["Berberine","Alkaloids","Metabolic Effects","Diabetes Mellitus","Anti-inflammatory","AMP-Activated Protein Kinase","Cholesterol-lowering","Anticancer","Glucose Metabolism","Traditional Medicine"],"openalex_id":"https://openalex.org/T12059","source_created_date":"2024-01-23T15:27:12","source_updated_date":"2026-10-17T03:02:00","subfield_id":"2736","url":"/topics/T12059","works_api_url":"https://api.openalex.org/works?filter=topics.id:T12059","works_count":9996,"label":"Berberine and alkaloids research","provider":"openalex","revision":"ed87921814299190","taxonomy_revision":"f050b5d4780b1289","title":"Berberine and alkaloids research","kind":"topic-directory","aeo_cohort":"topic-directory","catalogue_revision":"f050b5d4780b1289","numeric_address":"36249559416873386","address_version":"morton4x16-v1","coordinates":[4,27,2736,12059],"answer_status":"Directory metadata; local answer requires separate source review","truth_status":"Subject descriptor, not a factual answer or a demonstrated knowledge gap","reviewed_answer":null}