{"cited_by_count":473098,"description":"This cluster of papers explores the physiological effects of space travel and microgravity on the human body, including topics such as bone loss, muscle atrophy, immune system dysregulation, cardiovascular function, cytoskeletal changes, and neurological effects. It also addresses the psychological challenges faced by astronauts during long-duration space missions.","display_name":"Spaceflight effects on biology","domain_id":"4","external_ids":{"openalex":"https://openalex.org/T12005","wikipedia":"https://en.wikipedia.org/wiki/Space_physiology"},"field_id":"27","id":"T12005","keywords":[{"display_name":"microgravity","id":"microgravity","score":0.4255,"url":"https://openalex.org/keywords/microgravity"},{"display_name":"spaceflight","id":"spaceflight","score":0.4207,"url":"https://openalex.org/keywords/spaceflight"},{"display_name":"simulated microgravity","id":"simulated-microgravity","score":0.7286,"url":"https://openalex.org/keywords/simulated-microgravity"},{"display_name":"long-duration spaceflight","id":"long-duration-spaceflight","score":0.5139,"url":"https://openalex.org/keywords/long-duration-spaceflight"},{"display_name":"astronaut health","id":"astronaut-health","score":0.7079,"url":"https://openalex.org/keywords/astronaut-health"},{"display_name":"space medicine","id":"space-medicine","score":0.6493,"url":"https://openalex.org/keywords/space-medicine"},{"display_name":"space biology","id":"space-biology","score":0.6938,"url":"https://openalex.org/keywords/space-biology"},{"display_name":"astronauts","id":"astronauts","score":0.3453,"url":"https://openalex.org/keywords/astronauts"},{"display_name":"hypergravity","id":"hypergravity","score":0.6704,"url":"https://openalex.org/keywords/hypergravity"},{"display_name":"bed rest","id":"bed-rest","score":0.2392,"url":"https://openalex.org/keywords/bed-rest"},{"display_name":"hindlimb unloading","id":"hindlimb-unloading","score":0.5055,"url":"https://openalex.org/keywords/hindlimb-unloading"},{"display_name":"head-down bed rest","id":"head-down-bed-rest","score":0.8993,"url":"https://openalex.org/keywords/head-down-bed-rest"},{"display_name":"spaceflight countermeasures","id":"spaceflight-countermeasures","score":0.8208,"url":"https://openalex.org/keywords/spaceflight-countermeasures"},{"display_name":"aerospace medicine","id":"aerospace-medicine","score":0.5697,"url":"https://openalex.org/keywords/aerospace-medicine"},{"display_name":"parabolic flight","id":"parabolic-flight","score":0.3564,"url":"https://openalex.org/keywords/parabolic-flight"},{"display_name":"head-down tilt","id":"head-down-tilt","score":0.5538,"url":"https://openalex.org/keywords/head-down-tilt"},{"display_name":"artificial gravity","id":"artificial-gravity","score":0.5415,"url":"https://openalex.org/keywords/artificial-gravity"},{"display_name":"cosmonauts","id":"cosmonauts","score":0.4313,"url":"https://openalex.org/keywords/cosmonauts"},{"display_name":"spaceflight physiology","id":"spaceflight-physiology","score":0.8636,"url":"https://openalex.org/keywords/spaceflight-physiology"},{"display_name":"cardiovascular deconditioning","id":"cardiovascular-deconditioning","score":0.8198,"url":"https://openalex.org/keywords/cardiovascular-deconditioning"},{"display_name":"spaceflight adaptation","id":"spaceflight-adaptation","score":0.7849,"url":"https://openalex.org/keywords/spaceflight-adaptation"},{"display_name":"clinostat","id":"clinostat","score":0.7689,"url":"https://openalex.org/keywords/clinostat"},{"display_name":"gravity sensing","id":"gravity-sensing","score":0.3118,"url":"https://openalex.org/keywords/gravity-sensing"},{"display_name":"hypokinesia","id":"hypokinesia","score":0.2059,"url":"https://openalex.org/keywords/hypokinesia"},{"display_name":"altered gravity","id":"altered-gravity","score":0.7423,"url":"https://openalex.org/keywords/altered-gravity"}],"legacy_keywords":["Microgravity","Spaceflight","Physiological Adaptations","Bone Loss","Muscle Atrophy","Immune System","Cardiovascular Function","Cytoskeletal Changes","Neurological Effects","Psychological Challenges"],"openalex_id":"https://openalex.org/T12005","source_created_date":"2024-01-23T15:27:12","source_updated_date":"2026-10-17T03:02:00","subfield_id":"2737","url":"/topics/T12005","works_api_url":"https://api.openalex.org/works?filter=topics.id:T12005","works_count":61633,"label":"Spaceflight effects on biology","provider":"openalex","revision":"5b6a6416a672ff90","taxonomy_revision":"f050b5d4780b1289","title":"Spaceflight effects on biology","kind":"topic-directory","aeo_cohort":"topic-directory","catalogue_revision":"f050b5d4780b1289","numeric_address":"36249527346669870","address_version":"morton4x16-v1","coordinates":[4,27,2737,12005],"answer_status":"Directory metadata; local answer requires separate source review","truth_status":"Subject descriptor, not a factual answer or a demonstrated knowledge gap","reviewed_answer":null}