{"cited_by_count":450054,"description":"This cluster of papers explores the genetic and physiological adaptations of humans and other vertebrates to high-altitude environments, focusing on topics such as hypoxia, acute mountain sickness, erythropoietin response, oxidative stress, pulmonary edema, and the effects of endurance training. The research covers a wide range of aspects including molecular, systemic, and cellular responses to high-altitude conditions.","display_name":"High Altitude and Hypoxia","domain_id":"1","external_ids":{"openalex":"https://openalex.org/T11968","wikipedia":"https://en.wikipedia.org/wiki/Effects_of_high_altitude_on_humans"},"field_id":"13","id":"T11968","keywords":[{"display_name":"high altitude","id":"high-altitude","score":0.4912,"url":"https://openalex.org/keywords/high-altitude"},{"display_name":"high-altitude adaptation","id":"high-altitude-adaptation","score":0.6758,"url":"https://openalex.org/keywords/high-altitude-adaptation"},{"display_name":"acute mountain sickness","id":"acute-mountain-sickness","score":0.9232,"url":"https://openalex.org/keywords/acute-mountain-sickness"},{"display_name":"hypobaric hypoxia","id":"hypobaric-hypoxia","score":0.6016,"url":"https://openalex.org/keywords/hypobaric-hypoxia"},{"display_name":"altitude training","id":"altitude-training","score":0.7382,"url":"https://openalex.org/keywords/altitude-training"},{"display_name":"altitude sickness","id":"altitude-sickness","score":0.7955,"url":"https://openalex.org/keywords/altitude-sickness"},{"display_name":"high altitude pulmonary edema","id":"high-altitude-pulmonary-edema","score":0.8656,"url":"https://openalex.org/keywords/high-altitude-pulmonary-edema"},{"display_name":"hypoxia adaptation","id":"hypoxia-adaptation","score":0.3639,"url":"https://openalex.org/keywords/hypoxia-adaptation"},{"display_name":"normobaric hypoxia","id":"normobaric-hypoxia","score":0.648,"url":"https://openalex.org/keywords/normobaric-hypoxia"},{"display_name":"acute hypoxia","id":"acute-hypoxia","score":0.3526,"url":"https://openalex.org/keywords/acute-hypoxia"},{"display_name":"simulated altitude","id":"simulated-altitude","score":0.6858,"url":"https://openalex.org/keywords/simulated-altitude"},{"display_name":"high-altitude hypoxia","id":"high-altitude-hypoxia","score":0.7092,"url":"https://openalex.org/keywords/high-altitude-hypoxia"},{"display_name":"hypoxic training","id":"hypoxic-training","score":0.674,"url":"https://openalex.org/keywords/hypoxic-training"},{"display_name":"high-altitude medicine","id":"high-altitude-medicine","score":0.7262,"url":"https://openalex.org/keywords/high-altitude-medicine"},{"display_name":"Mount Everest","id":"mount-everest","score":0.2076,"url":"https://openalex.org/keywords/mount-everest"},{"display_name":"high altitude exposure","id":"high-altitude-exposure","score":0.6996,"url":"https://openalex.org/keywords/high-altitude-exposure"},{"display_name":"high-altitude cerebral edema","id":"high-altitude-cerebral-edema","score":0.9263,"url":"https://openalex.org/keywords/high-altitude-cerebral-edema"},{"display_name":"high-altitude mountaineering","id":"high-altitude-mountaineering","score":0.466,"url":"https://openalex.org/keywords/high-altitude-mountaineering"},{"display_name":"altitude physiology","id":"altitude-physiology","score":0.842,"url":"https://openalex.org/keywords/altitude-physiology"},{"display_name":"high altitude acclimatization","id":"high-altitude-acclimatization","score":0.8947,"url":"https://openalex.org/keywords/high-altitude-acclimatization"},{"display_name":"chronic mountain sickness","id":"chronic-mountain-sickness","score":0.8869,"url":"https://openalex.org/keywords/chronic-mountain-sickness"},{"display_name":"high-altitude physiology","id":"high-altitude-physiology","score":0.7538,"url":"https://openalex.org/keywords/high-altitude-physiology"},{"display_name":"high-altitude illness","id":"high-altitude-illness","score":0.8013,"url":"https://openalex.org/keywords/high-altitude-illness"},{"display_name":"altitude exposure","id":"altitude-exposure","score":0.6677,"url":"https://openalex.org/keywords/altitude-exposure"},{"display_name":"hypobaric chamber","id":"hypobaric-chamber","score":0.6009,"url":"https://openalex.org/keywords/hypobaric-chamber"}],"legacy_keywords":["High Altitude","Adaptation","Hypoxia","Genetic","Physiological","Acute Mountain Sickness","Erythropoietin","Oxidative Stress","Pulmonary Edema","Endurance Training"],"openalex_id":"https://openalex.org/T11968","source_created_date":"2024-01-23T15:27:12","source_updated_date":"2026-10-17T03:02:00","subfield_id":"1311","url":"/topics/T11968","works_api_url":"https://api.openalex.org/works?filter=topics.id:T11968","works_count":48104,"label":"High Altitude and Hypoxia","provider":"openalex","revision":"cdd9288b63153916","taxonomy_revision":"f050b5d4780b1289","title":"High Altitude and Hypoxia","kind":"topic-directory","aeo_cohort":"topic-directory","catalogue_revision":"f050b5d4780b1289","numeric_address":"36183297864525383","address_version":"morton4x16-v1","coordinates":[1,13,1311,11968],"answer_status":"Directory metadata; local answer requires separate source review","truth_status":"Subject descriptor, not a factual answer or a demonstrated knowledge gap","reviewed_answer":null}