{"cited_by_count":478407,"description":"This cluster of papers focuses on the diagnosis, evaluation, and treatment of hyponatremia, with a particular emphasis on its association with heart failure, elderly patients, osteoporosis, and inappropriate antidiuresis. The role of vasopressin and copeptin as biomarkers, as well as the neurological complications associated with hyponatremia, are also explored.","display_name":"Electrolyte and hormonal disorders","domain_id":"4","external_ids":{"openalex":"https://openalex.org/T11967","wikipedia":"https://en.wikipedia.org/wiki/Hyponatremia"},"field_id":"27","id":"T11967","keywords":[{"display_name":"hyponatremia","id":"hyponatremia","score":0.5009,"url":"https://openalex.org/keywords/hyponatremia"},{"display_name":"syndrome of inappropriate antidiuretic hormone secretion","id":"syndrome-of-inappropriate-antidiuretic-hormone-secretion","score":0.7401,"url":"https://openalex.org/keywords/syndrome-of-inappropriate-antidiuretic-hormone-secretion"},{"display_name":"hypernatremia","id":"hypernatremia","score":0.456,"url":"https://openalex.org/keywords/hypernatremia"},{"display_name":"diabetes insipidus","id":"diabetes-insipidus","score":0.3038,"url":"https://openalex.org/keywords/diabetes-insipidus"},{"display_name":"serum sodium","id":"serum-sodium","score":0.2607,"url":"https://openalex.org/keywords/serum-sodium"},{"display_name":"desmopressin","id":"desmopressin","score":0.2239,"url":"https://openalex.org/keywords/desmopressin"},{"display_name":"polyuria","id":"polyuria","score":0.2495,"url":"https://openalex.org/keywords/polyuria"},{"display_name":"central pontine myelinolysis","id":"osmotic-demyelination-syndrome","score":0.6123,"url":"https://openalex.org/keywords/osmotic-demyelination-syndrome"},{"display_name":"central diabetes insipidus","id":"central-diabetes-insipidus","score":0.4408,"url":"https://openalex.org/keywords/central-diabetes-insipidus"},{"display_name":"water intoxication","id":"water-intoxication","score":0.5891,"url":"https://openalex.org/keywords/water-intoxication"},{"display_name":"urine osmolality","id":"urine-osmolality","score":0.2545,"url":"https://openalex.org/keywords/urine-osmolality"},{"display_name":"polydipsia","id":"polydipsia","score":0.2898,"url":"https://openalex.org/keywords/polydipsia"},{"display_name":"vasopressin receptor antagonists","id":"vasopressin-receptor-antagonists","score":0.4404,"url":"https://openalex.org/keywords/vasopressin-receptor-antagonists"},{"display_name":"fluid restriction","id":"fluid-restriction","score":0.2153,"url":"https://openalex.org/keywords/fluid-restriction"},{"display_name":"plasma osmolality","id":"plasma-osmolality","score":0.2275,"url":"https://openalex.org/keywords/plasma-osmolality"},{"display_name":"sodium imbalance","id":"sodium-imbalance","score":0.8023,"url":"https://openalex.org/keywords/sodium-imbalance"},{"display_name":"nephrogenic diabetes insipidus","id":"nephrogenic-diabetes-insipidus","score":0.3412,"url":"https://openalex.org/keywords/nephrogenic-diabetes-insipidus"},{"display_name":"tolvaptan","id":"tolvaptan","score":0.3059,"url":"https://openalex.org/keywords/tolvaptan"},{"display_name":"drug-induced hyponatremia","id":"drug-induced-hyponatremia","score":0.9339,"url":"https://openalex.org/keywords/drug-induced-hyponatremia"},{"display_name":"cerebral salt wasting syndrome","id":"cerebral-salt-wasting-syndrome","score":0.7798,"url":"https://openalex.org/keywords/cerebral-salt-wasting-syndrome"},{"display_name":"water metabolism","id":"water-metabolism","score":0.2547,"url":"https://openalex.org/keywords/water-metabolism"},{"display_name":"water diuresis","id":"water-diuresis","score":0.3639,"url":"https://openalex.org/keywords/water-diuresis"},{"display_name":"plasma sodium","id":"plasma-sodium","score":0.2366,"url":"https://openalex.org/keywords/plasma-sodium"},{"display_name":"serum osmolality","id":"serum-osmolality","score":0.2738,"url":"https://openalex.org/keywords/serum-osmolality"},{"display_name":"water deprivation test","id":"water-deprivation-test","score":0.6012,"url":"https://openalex.org/keywords/water-deprivation-test"}],"legacy_keywords":["Hyponatremia","Vasopressin","Copeptin","Heart Failure","Diagnosis","Treatment","Elderly","Osteoporosis","Inappropriate Antidiuresis","Neurological Complications"],"openalex_id":"https://openalex.org/T11967","source_created_date":"2024-01-23T15:27:12","source_updated_date":"2026-10-17T03:02:00","subfield_id":"2740","url":"/topics/T11967","works_api_url":"https://api.openalex.org/works?filter=topics.id:T11967","works_count":52110,"label":"Electrolyte and hormonal disorders","provider":"openalex","revision":"544359108a94508d","taxonomy_revision":"f050b5d4780b1289","title":"Electrolyte and hormonal disorders","kind":"topic-directory","aeo_cohort":"topic-directory","catalogue_revision":"f050b5d4780b1289","numeric_address":"36249527213010346","address_version":"morton4x16-v1","coordinates":[4,27,2740,11967],"answer_status":"Directory metadata; local answer requires separate source review","truth_status":"Subject descriptor, not a factual answer or a demonstrated knowledge gap","reviewed_answer":null}