{"cited_by_count":482986,"description":"This cluster of papers focuses on the biomedical applications of silk biomaterials, particularly silk fibroin, in areas such as tissue engineering, drug delivery, and understanding the mechanical properties and protein structure of silk. It also covers topics related to spider silk and regenerated silk, as well as the genome sequencing and biodegradation of silk biomaterials.","display_name":"Silk-based biomaterials and applications","domain_id":"3","external_ids":{"openalex":"https://openalex.org/T11966","wikipedia":"https://en.wikipedia.org/wiki/Silk#Biomedical_and_biotechnological_applications"},"field_id":"25","id":"T11966","keywords":[{"display_name":"silk fibroin","id":"silk-fibroin","score":0.5735,"url":"https://openalex.org/keywords/silk-fibroin"},{"display_name":"spider silk","id":"spider-silk","score":0.5885,"url":"https://openalex.org/keywords/spider-silk"},{"display_name":"silk proteins","id":"silk-proteins","score":0.7025,"url":"https://openalex.org/keywords/silk-proteins"},{"display_name":"sericin","id":"sericin","score":0.4099,"url":"https://openalex.org/keywords/sericin"},{"display_name":"spider dragline silk","id":"spider-dragline-silk","score":0.8473,"url":"https://openalex.org/keywords/spider-dragline-silk"},{"display_name":"silk fibers","id":"silk-fibers","score":0.3339,"url":"https://openalex.org/keywords/silk-fibers"},{"display_name":"silk gland","id":"silk-gland","score":0.2514,"url":"https://openalex.org/keywords/silk-gland"},{"display_name":"spider silk proteins","id":"spider-silk-proteins","score":0.7622,"url":"https://openalex.org/keywords/spider-silk-proteins"},{"display_name":"regenerated silk fibroin","id":"regenerated-silk-fibroin","score":0.7832,"url":"https://openalex.org/keywords/regenerated-silk-fibroin"},{"display_name":"silk sericin","id":"silk-sericin","score":0.5235,"url":"https://openalex.org/keywords/silk-sericin"},{"display_name":"spidroin","id":"spidroin","score":0.8338,"url":"https://openalex.org/keywords/spidroin"},{"display_name":"recombinant spider silk","id":"recombinant-spider-silk-proteins","score":0.8773,"url":"https://openalex.org/keywords/recombinant-spider-silk-proteins"},{"display_name":"Bombyx mori silk","id":"bombyx-mori-silk","score":0.6327,"url":"https://openalex.org/keywords/bombyx-mori-silk"},{"display_name":"silk fibroin films","id":"silk-fibroin-films","score":0.7817,"url":"https://openalex.org/keywords/silk-fibroin-films"},{"display_name":"silk fibroin hydrogel","id":"silk-fibroin-hydrogel","score":0.5965,"url":"https://openalex.org/keywords/silk-fibroin-hydrogel"},{"display_name":"silkworm silk","id":"silkworm-silk","score":0.7396,"url":"https://openalex.org/keywords/silkworm-silk"},{"display_name":"Nephila clavipes","id":"nephila-clavipes","score":0.5365,"url":"https://openalex.org/keywords/nephila-clavipes"},{"display_name":"silk fibroin scaffolds","id":"silk-fibroin-scaffolds","score":0.5377,"url":"https://openalex.org/keywords/silk-fibroin-scaffolds"},{"display_name":"silk mechanical properties","id":"mechanical-properties-of-silk","score":0.8474,"url":"https://openalex.org/keywords/mechanical-properties-of-silk"},{"display_name":"Bombyx mori silk fibroin","id":"bombyx-mori-silk-fibroin","score":0.8313,"url":"https://openalex.org/keywords/bombyx-mori-silk-fibroin"},{"display_name":"silk spinning","id":"silk-spinning","score":0.2385,"url":"https://openalex.org/keywords/silk-spinning"},{"display_name":"silk films","id":"silk-films","score":0.744,"url":"https://openalex.org/keywords/silk-films"},{"display_name":"silkworm cocoon","id":"silkworm-cocoon","score":0.256,"url":"https://openalex.org/keywords/silkworm-cocoon"},{"display_name":"silk fibroin nanoparticles","id":"silk-fibroin-nanoparticles","score":0.5665,"url":"https://openalex.org/keywords/silk-fibroin-nanoparticles"},{"display_name":"silk cocoon","id":"silk-cocoon","score":0.2409,"url":"https://openalex.org/keywords/silk-cocoon"}],"legacy_keywords":["Silk Fibroin","Biomaterials","Tissue Engineering","Spider Silk","Regenerated Silk","Drug Delivery","Mechanical Properties","Genome Sequencing","Biodegradation","Protein Structure"],"openalex_id":"https://openalex.org/T11966","source_created_date":"2024-01-23T15:27:12","source_updated_date":"2026-10-17T03:02:00","subfield_id":"2502","url":"/topics/T11966","works_api_url":"https://api.openalex.org/works?filter=topics.id:T11966","works_count":20982,"label":"Silk-based biomaterials and applications","provider":"openalex","revision":"646450ce03524542","taxonomy_revision":"f050b5d4780b1289","title":"Silk-based biomaterials and applications","kind":"topic-directory","aeo_cohort":"topic-directory","catalogue_revision":"f050b5d4780b1289","numeric_address":"36249269577624787","address_version":"morton4x16-v1","coordinates":[3,25,2502,11966],"answer_status":"Directory metadata; local answer requires separate source review","truth_status":"Subject descriptor, not a factual answer or a demonstrated knowledge gap","reviewed_answer":null}