{"cited_by_count":417143,"description":"This cluster of papers focuses on the chemotherapy-induced peripheral neuropathy (CIPN) experienced by cancer patients, particularly in the context of breast cancer treatment. It covers various aspects such as the neurotoxic effects of taxanes and oxaliplatin, neuroprotective strategies, and the impact of CIPN on the quality of life of patients. Additionally, it discusses the use of microtubule-targeting agents like Eribulin Mesylate in cancer treatment.","display_name":"Cancer Treatment and Pharmacology","domain_id":"4","external_ids":{"openalex":"https://openalex.org/T11752","wikipedia":"https://en.wikipedia.org/wiki/Chemotherapy-induced_peripheral_neuropathy"},"field_id":"27","id":"T11752","keywords":[{"display_name":"chemotherapy-induced peripheral neuropathy","id":"chemotherapy-induced-peripheral-neuropathy","score":0.719,"url":"https://openalex.org/keywords/chemotherapy-induced-peripheral-neuropathy"},{"display_name":"chemotherapy-induced neurotoxicity","id":"chemotherapy-induced-neurotoxicity","score":0.3928,"url":"https://openalex.org/keywords/chemotherapy-induced-neurotoxicity"},{"display_name":"eribulin","id":"eribulin","score":0.3085,"url":"https://openalex.org/keywords/eribulin"},{"display_name":"neuropathy prevention","id":"neuropathy-prevention","score":0.6583,"url":"https://openalex.org/keywords/neuropathy-prevention"},{"display_name":"taxane resistance","id":"taxane-resistance","score":0.2345,"url":"https://openalex.org/keywords/taxane-resistance"},{"display_name":"anthracycline resistance","id":"anthracycline-resistance","score":0.241,"url":"https://openalex.org/keywords/anthracycline-resistance"},{"display_name":"ixabepilone","id":"ixabepilone","score":0.4594,"url":"https://openalex.org/keywords/ixabepilone"},{"display_name":"drug-induced neuropathy","id":"drug-induced-neuropathy","score":0.2186,"url":"https://openalex.org/keywords/drug-induced-neuropathy"},{"display_name":"oxaliplatin-induced peripheral neuropathy","id":"oxaliplatin-induced-peripheral-neuropathy","score":0.5579,"url":"https://openalex.org/keywords/oxaliplatin-induced-peripheral-neuropathy"},{"display_name":"paclitaxel-induced peripheral neuropathy","id":"paclitaxel-induced-peripheral-neuropathy","score":0.596,"url":"https://openalex.org/keywords/paclitaxel-induced-peripheral-neuropathy"},{"display_name":"peripheral neurotoxicity","id":"peripheral-neurotoxicity","score":0.4644,"url":"https://openalex.org/keywords/peripheral-neurotoxicity"},{"display_name":"epothilones","id":"epothilones","score":0.2537,"url":"https://openalex.org/keywords/epothilones"},{"display_name":"eribulin mesylate","id":"eribulin-mesylate","score":0.56,"url":"https://openalex.org/keywords/eribulin-mesylate"},{"display_name":"peripheral sensory neuropathy","id":"peripheral-sensory-neuropathy","score":0.2029,"url":"https://openalex.org/keywords/peripheral-sensory-neuropathy"},{"display_name":"neurotoxic chemotherapy","id":"neurotoxic-chemotherapy","score":0.7968,"url":"https://openalex.org/keywords/neurotoxic-chemotherapy"},{"display_name":"anthracycline-pretreated patients","id":"anthracycline-pretreated-patients","score":0.653,"url":"https://openalex.org/keywords/anthracycline-pretreated-patients"},{"display_name":"anthracycline-refractory disease","id":"anthracycline-refractory-disease","score":0.5174,"url":"https://openalex.org/keywords/anthracycline-refractory-disease"},{"display_name":"taxane-induced peripheral neuropathy","id":"taxane-induced-peripheral-neuropathy","score":0.8883,"url":"https://openalex.org/keywords/taxane-induced-peripheral-neuropathy"},{"display_name":"drug-induced peripheral neuropathy","id":"drug-induced-peripheral-neuropathy","score":0.4089,"url":"https://openalex.org/keywords/drug-induced-peripheral-neuropathy"},{"display_name":"neuropathy severity","id":"neuropathy-severity","score":0.243,"url":"https://openalex.org/keywords/neuropathy-severity"},{"display_name":"EORTC QLQ-CIPN20","id":"eortc-qlq-cipn20","score":0.9432,"url":"https://openalex.org/keywords/eortc-qlq-cipn20"},{"display_name":"chemotherapy-induced neuropathic pain","id":"chemotherapy-induced-neuropathic-pain","score":0.3,"url":"https://openalex.org/keywords/chemotherapy-induced-neuropathic-pain"},{"display_name":"taxane-refractory disease","id":"taxane-refractory-disease","score":0.4615,"url":"https://openalex.org/keywords/taxane-refractory-disease"},{"display_name":"neuropathy treatment","id":"neuropathy-treatment","score":0.2163,"url":"https://openalex.org/keywords/neuropathy-treatment"},{"display_name":"Total Neuropathy Score","id":"total-neuropathy-score","score":0.6238,"url":"https://openalex.org/keywords/total-neuropathy-score"}],"legacy_keywords":["Chemotherapy-Induced Peripheral Neuropathy","Taxanes","Oxaliplatin","Paclitaxel","Neurotoxicity","Metastatic Breast Cancer","Eribulin Mesylate","Neuroprotective Strategies","Microtubule-Targeting Agents","Quality of Life"],"openalex_id":"https://openalex.org/T11752","source_created_date":"2024-01-23T15:27:11","source_updated_date":"2026-10-17T03:02:00","subfield_id":"2730","url":"/topics/T11752","works_api_url":"https://api.openalex.org/works?filter=topics.id:T11752","works_count":29158,"label":"Cancer Treatment and Pharmacology","provider":"openalex","revision":"8419903a1dab6f7b","taxonomy_revision":"f050b5d4780b1289","title":"Cancer Treatment and Pharmacology","kind":"topic-directory","aeo_cohort":"topic-directory","catalogue_revision":"f050b5d4780b1289","numeric_address":"36249011950379362","address_version":"morton4x16-v1","coordinates":[4,27,2730,11752],"answer_status":"Directory metadata; local answer requires separate source review","truth_status":"Subject descriptor, not a factual answer or a demonstrated knowledge gap","reviewed_answer":null}