{"cited_by_count":1132451,"description":"This cluster of papers explores the developmental origins of adult health and disease, focusing on the impact of in utero and early-life conditions on long-term health outcomes. The research covers topics such as fetal programming, metabolic syndrome, epigenetic mechanisms, catch-up growth, hypertension risk associated with low birth weight, and the role of glucocorticoid programming in chronic disease development.","display_name":"Birth, Development, and Health","domain_id":"4","external_ids":{"openalex":"https://openalex.org/T11629","wikipedia":"https://en.wikipedia.org/wiki/Developmental_Origins_of_Health_and_Disease"},"field_id":"27","id":"T11629","keywords":[{"display_name":"fetal programming","id":"fetal-programming","score":0.6362,"url":"https://openalex.org/keywords/fetal-programming"},{"display_name":"developmental origins of health and disease","id":"developmental-origins-of-health-and-disease","score":0.6011,"url":"https://openalex.org/keywords/developmental-origins-of-health-and-disease"},{"display_name":"developmental programming","id":"developmental-programming","score":0.3826,"url":"https://openalex.org/keywords/developmental-programming"},{"display_name":"intrauterine environment","id":"intrauterine-environment","score":0.3686,"url":"https://openalex.org/keywords/intrauterine-environment"},{"display_name":"catch-up growth","id":"catch-up-growth","score":0.2081,"url":"https://openalex.org/keywords/catch-up-growth"},{"display_name":"maternal undernutrition","id":"maternal-undernutrition","score":0.4516,"url":"https://openalex.org/keywords/maternal-undernutrition"},{"display_name":"metabolic programming","id":"metabolic-programming","score":0.4868,"url":"https://openalex.org/keywords/metabolic-programming"},{"display_name":"maternal malnutrition","id":"maternal-malnutrition","score":0.2619,"url":"https://openalex.org/keywords/maternal-malnutrition"},{"display_name":"maternal high-fat diet","id":"maternal-high-fat-diet","score":0.5733,"url":"https://openalex.org/keywords/maternal-high-fat-diet"},{"display_name":"early life nutrition","id":"early-life-nutrition","score":0.2365,"url":"https://openalex.org/keywords/early-life-nutrition"},{"display_name":"fetal origins of adult disease","id":"fetal-origins-of-adult-disease","score":0.7567,"url":"https://openalex.org/keywords/fetal-origins-of-adult-disease"},{"display_name":"fetal malnutrition","id":"fetal-malnutrition","score":0.5964,"url":"https://openalex.org/keywords/fetal-malnutrition"},{"display_name":"prenatal programming","id":"prenatal-programming","score":0.5058,"url":"https://openalex.org/keywords/prenatal-programming"},{"display_name":"maternal protein restriction","id":"maternal-protein-restriction","score":0.7038,"url":"https://openalex.org/keywords/maternal-protein-restriction"},{"display_name":"Barker hypothesis","id":"barker-hypothesis","score":0.6781,"url":"https://openalex.org/keywords/barker-hypothesis"},{"display_name":"fetal nutrition","id":"fetal-nutrition","score":0.3145,"url":"https://openalex.org/keywords/fetal-nutrition"},{"display_name":"prenatal malnutrition","id":"prenatal-malnutrition","score":0.6413,"url":"https://openalex.org/keywords/prenatal-malnutrition"},{"display_name":"epigenetic programming","id":"epigenetic-programming","score":0.2828,"url":"https://openalex.org/keywords/epigenetic-programming"},{"display_name":"fetal origins of disease","id":"fetal-origins-of-disease","score":0.7606,"url":"https://openalex.org/keywords/fetal-origins-of-disease"},{"display_name":"maternal overnutrition","id":"maternal-overnutrition","score":0.6772,"url":"https://openalex.org/keywords/maternal-overnutrition"},{"display_name":"offspring obesity","id":"offspring-obesity","score":0.467,"url":"https://openalex.org/keywords/offspring-obesity"},{"display_name":"nephron number","id":"nephron-number","score":0.2866,"url":"https://openalex.org/keywords/nephron-number"},{"display_name":"adult offspring","id":"adult-offspring","score":0.3433,"url":"https://openalex.org/keywords/adult-offspring"},{"display_name":"intrauterine programming","id":"intrauterine-programming","score":0.608,"url":"https://openalex.org/keywords/intrauterine-programming"},{"display_name":"birth size","id":"birth-size","score":0.2522,"url":"https://openalex.org/keywords/birth-size"}],"legacy_keywords":["Fetal Programming","Early-Life Conditions","Metabolic Syndrome","Epigenetic Mechanisms","In Utero Nutrition","Catch-Up Growth","Hypertension Risk","Low Birth Weight","Glucocorticoid Programming","Chronic Disease"],"openalex_id":"https://openalex.org/T11629","source_created_date":"2024-01-23T15:27:11","source_updated_date":"2026-10-17T03:02:00","subfield_id":"2735","url":"/topics/T11629","works_api_url":"https://api.openalex.org/works?filter=topics.id:T11629","works_count":55803,"label":"Birth, Development, and Health","provider":"openalex","revision":"9ff3886bee9aa160","taxonomy_revision":"f050b5d4780b1289","title":"Birth, Development, and Health","kind":"topic-directory","aeo_cohort":"topic-directory","catalogue_revision":"f050b5d4780b1289","numeric_address":"36249009802898798","address_version":"morton4x16-v1","coordinates":[4,27,2735,11629],"answer_status":"Directory metadata; local answer requires separate source review","truth_status":"Subject descriptor, not a factual answer or a demonstrated knowledge gap","reviewed_answer":null}