{"cited_by_count":737674,"description":"This cluster of papers focuses on the catalytic carbene chemistry in organic synthesis, particularly on the use of donor-acceptor cyclopropanes, diazo compounds, and metal-catalyzed reactions. It covers topics such as enantioselective synthesis, site-selective functionalization, and the development of artificial metalloenzymes for carbene transfer reactions.","display_name":"Cyclopropane Reaction Mechanisms","domain_id":"3","external_ids":{"openalex":"https://openalex.org/T11611","wikipedia":"https://en.wikipedia.org/wiki/Carbene_chemistry"},"field_id":"16","id":"T11611","keywords":[{"display_name":"cyclopropanation","id":"cyclopropanation","score":0.5297,"url":"https://openalex.org/keywords/cyclopropanation"},{"display_name":"cyclopropanes","id":"cyclopropanes","score":0.3391,"url":"https://openalex.org/keywords/cyclopropanes"},{"display_name":"diazo compounds","id":"diazo-compounds","score":0.4564,"url":"https://openalex.org/keywords/diazo-compounds"},{"display_name":"cyclopropane ring opening","id":"cyclopropane-ring-opening","score":0.5534,"url":"https://openalex.org/keywords/cyclopropane-ring-opening"},{"display_name":"diazomethane","id":"diazomethane","score":0.2305,"url":"https://openalex.org/keywords/diazomethane"},{"display_name":"cyclopropenes","id":"cyclopropenes","score":0.4801,"url":"https://openalex.org/keywords/cyclopropenes"},{"display_name":"vinylcyclopropanes","id":"vinylcyclopropanes","score":0.5596,"url":"https://openalex.org/keywords/vinylcyclopropanes"},{"display_name":"ethyl diazoacetate","id":"ethyl-diazoacetate","score":0.5945,"url":"https://openalex.org/keywords/ethyl-diazoacetate"},{"display_name":"rhodium(II) catalysis","id":"rhodium-ii-catalysis","score":0.6333,"url":"https://openalex.org/keywords/rhodium-ii-catalysis"},{"display_name":"donor-acceptor cyclopropanes","id":"donor-acceptor-cyclopropanes","score":0.8362,"url":"https://openalex.org/keywords/donor-acceptor-cyclopropanes"},{"display_name":"asymmetric cyclopropanation","id":"asymmetric-cyclopropanation","score":0.7886,"url":"https://openalex.org/keywords/asymmetric-cyclopropanation"},{"display_name":"diazoalkanes","id":"diazoalkanes","score":0.4508,"url":"https://openalex.org/keywords/diazoalkanes"},{"display_name":"methylenecyclopropanes","id":"methylenecyclopropanes","score":0.5987,"url":"https://openalex.org/keywords/methylenecyclopropanes"},{"display_name":"C-H insertion","id":"c-h-insertion","score":0.3256,"url":"https://openalex.org/keywords/c-h-insertion"},{"display_name":"cyclopropane formation","id":"cyclopropane-formation","score":0.3913,"url":"https://openalex.org/keywords/cyclopropane-formation"},{"display_name":"diazo esters","id":"diazo-esters","score":0.6072,"url":"https://openalex.org/keywords/diazo-esters"},{"display_name":"cyclopropanols","id":"cyclopropanols","score":0.6029,"url":"https://openalex.org/keywords/cyclopropanols"},{"display_name":"cyclopropyl ketones","id":"cyclopropyl-ketones","score":0.588,"url":"https://openalex.org/keywords/cyclopropyl-ketones"},{"display_name":"dichlorocarbene","id":"dichlorocarbene","score":0.3553,"url":"https://openalex.org/keywords/dichlorocarbene"},{"display_name":"intramolecular cyclopropanation","id":"intramolecular-cyclopropanation","score":0.7757,"url":"https://openalex.org/keywords/intramolecular-cyclopropanation"},{"display_name":"diazoketones","id":"diazoketones","score":0.3806,"url":"https://openalex.org/keywords/diazoketones"},{"display_name":"carbene insertion","id":"carbene-insertion","score":0.3644,"url":"https://openalex.org/keywords/carbene-insertion"},{"display_name":"diazoacetates","id":"diazoacetates","score":0.6455,"url":"https://openalex.org/keywords/diazoacetates"},{"display_name":"spirocyclopropanes","id":"spirocyclopropanes","score":0.5635,"url":"https://openalex.org/keywords/spirocyclopropanes"},{"display_name":"\u03b1-diazoketones","id":"alpha-diazoketones","score":0.6156,"url":"https://openalex.org/keywords/alpha-diazoketones"}],"legacy_keywords":["Carbene Chemistry","Cyclopropanation","Metal-Catalyzed Reactions","Donor-Acceptor Cyclopropanes","Enantioselective Synthesis","Rhodium-Catalyzed Reactions","Diazo Compounds","Artificial Metalloenzymes","Site-Selective Functionalization","Transition-Metal Chemistry"],"openalex_id":"https://openalex.org/T11611","source_created_date":"2024-01-23T15:27:11","source_updated_date":"2026-10-17T03:02:00","subfield_id":"1605","url":"/topics/T11611","works_api_url":"https://api.openalex.org/works?filter=topics.id:T11611","works_count":48208,"label":"Cyclopropane Reaction Mechanisms","provider":"openalex","revision":"177660b160efda97","taxonomy_revision":"f050b5d4780b1289","title":"Cyclopropane Reaction Mechanisms","kind":"topic-directory","aeo_cohort":"topic-directory","catalogue_revision":"f050b5d4780b1289","numeric_address":"36183038086513821","address_version":"morton4x16-v1","coordinates":[3,16,1605,11611],"answer_status":"Directory metadata; local answer requires separate source review","truth_status":"Subject descriptor, not a factual answer or a demonstrated knowledge gap","reviewed_answer":null}